Triterpenoid saponins and sapogenins: 1973–1978

Triterpenoid saponins from Anemone raddeana

“…as the ester glycosyl unit at C-28 of the aglycone were isolated not only from Anemone (Mazutani et al, 1984;Li et al, 2004), but also from other genera of the Ranunculaceae such as Pulsatilla (Shimizu et al, 1978) and Clematis (Chandel and Rastogi, 1980), as well as related families such as Lardizabalaceae (Chandel and Rastogi, 1980), Podophyllaceae (Agarwal and Rastogi, 1974) and Berberidaceae (Matsuo et al, 2009). However, saponins with the above trisaccharide in repeated chains as the ester glycosyl unit at C-28 of the aglycone were isolated only from Ranunculaceae (Wang et al, 1997;Li et al, 2008;Watanabe et al, 2003).…”

Saponins and Cardenolides

“…Triterpenoid saponins also are widespread in nature, being known from at least 90 families of plants (Agarwal and Rastogi, 1974;Chandel and Rastogi, 1980;de Mayo, 1959). These glycosides may possess from I to 10 sugar units (Agarwal and Rastogi, 1974).…”

“…This is the basis of a simple, reasonably specific test for the general presence of these compounds. Saponins also are detected by the Liebermann-Burchard test, which is useful for distinguishing between triterpenoid and steroidal saponins (Chandel and Rastogi, 1980 ported from more than 500 plants from at least 90 different families (Bondi et aI., 1973), these substances have heen isolated from all parts of plants: leaves, stems, roots bulbs, flowers, and froits, although they tend to be concentrated in the roots of many species. There is considerable seasonal variation in the amounts of saponins present, and often substantial variation within plant populations in the amount of compound is present.…”

Cholesterol-dependent hemolytic activity of Passiflora quadrangularis leaves

“…Each value is the mean of three replicates with a standard deviation of not more than 20% of the mean. tion or "unmasking" is a common feature of biologically active plant components such as saponins, many of which are present in the plant in inactive states that can be converted to active forms in situ or in vitro (5).…”

“…Furthermore, saponins have plasma cholesterol-lowering activity (5,12) and are widely utilized as a component of potent adjuvants to boost the immune response (16), principally when complexed with cholesterol (17). However, not all Passiflora species contain saponins in their leaves (18).…”