Triterpenes from balata resin

Tirucallane-Type Alkaloids from the Bark of Dysoxylum laxiracemosum

“…Similar to compounds 1-7, the 1 H and 13 C NMR data (Tables 2 and 3) of 8 showed the tirucallan-7-ene pattern in rings A-D. 6 In combination with the molecular formula C 26 H 35 NO 3 , based on its HRESIMS, the chemical shifts of the remaining four carbons [δ C 152.5 (s), 128.2 (d), 170.5(s), and 171.5(s)] and NH suggested the presence of a maleimide ring. 8 The structures of the known compounds, 3-oxo-24,25,26,27tetranortirucall-7-ene-23(21)-lactone (9), 9 3-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone (10), 9 β-amyrone, 10 β-amyrin, 11 24,25-epoxytirucall-7-ene-3,23-dione, 12 syringaresinol, 13 scopoletin, 14 3R-hydroxy-12-ursen-28-oic acid, 15 xylobuxin, 16 piscidinol B, 17 and β-amyrin acetate, 18 were determined by comparing their spectroscopic data with reported values. [9][10][11][12][13][14][15][16][17][18] Compounds 1-10 were evaluated for their cytotoxicity against the HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines by the MTT method, 19 and the results are shown in Table 4.…”

“…8 The structures of the known compounds, 3-oxo-24,25,26,27tetranortirucall-7-ene-23(21)-lactone (9), 9 3-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone (10), 9 β-amyrone, 10 β-amyrin, 11 24,25-epoxytirucall-7-ene-3,23-dione, 12 syringaresinol, 13 scopoletin, 14 3R-hydroxy-12-ursen-28-oic acid, 15 xylobuxin, 16 piscidinol B, 17 and β-amyrin acetate, 18 were determined by comparing their spectroscopic data with reported values. [9][10][11][12][13][14][15][16][17][18] Compounds 1-10 were evaluated for their cytotoxicity against the HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines by the MTT method, 19 and the results are shown in Table 4. The most potent cytotoxic compound was laxiracemosin E (5), while compound 1 also showed significant cytotoxicity against these cell lines.…”

“…The structures of the known compounds, 3-oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone ( 9 ), 3-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone ( 10 ), β-amyrone, β-amyrin, 24,25-epoxytirucall-7-ene-3,23-dione, syringaresinol, scopoletin, 3α-hydroxy-12-ursen-28-oic acid, xylobuxin, piscidinol B, and β-amyrin acetate, were determined by comparing their spectroscopic data with reported values. − …”

A Fernane-Type Triterpene from Sericostoma pauciflorum

“…The latter could be resolved through flash cc over Si gel using the same solvent system to yield ot-amyrin (12 mg) and ß-amyrin (10 mg), respectively. All were identified by comparison of physical and spectral data with those reported in the literature (8,9). The eluate from hexane-CHCl3 (7:3) yielded sericostinyl acetate [1]…”

24-Methylenecycloartanone

“…For its relative stereochemistry, see: Alves et al (2000); Ohta & Shimizu (1958). For general background the title compound and the plant Ainsliaea henryi, see: Anjaneyulu et al (1999); Boehme et al (1997); Chinese Materia Medica (2007); Ei-Dib et al (2004); Fiechi et al (1966); Gabrera & Seldes (1995); Jayasinghe et al (2001); Kojima et al (1985); Kolhe et al (1982); Lao et al (1984); Lawrie et al (1970); Li & Xue (1986); Manoharan et al (2005); Ohtsu et al (1998); Schulte et al (1979); Tachi et al (1971); Tandon & Rastogi (1976).…”