Trismus: Modern pathophysiological correlates

O'Leary, Margaret

doi:10.1016/0735-6757(90)90327-v

Cited by 18 publications

(16 citation statements)

References 39 publications

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“…The trigeminal motor nucleus arises from the pons and the motor component runs along the mandibular division of the trigeminal nerve. Patients with known focal central nervous system lesions of the trigeminal nerve system in the medulla and pons may have dissynergism of the masticatory muscles on the basis of clinical and EMG findings, leading to trismus [2, 16]. In our case, the MRI of the brain revealed acute infarcts in the central and left pons in addition to the bilateral frontal white matter lesions.…”

Section: Discussionmentioning

confidence: 70%

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Spontaneous NosocomialPseudomonas aeruginosaMeningitis Presenting as Trismus

Parr

Wheeler

Sharma

et al. 2017

Case Reports in Infectious Diseases

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We describe the case of a 78-year-old female receiving adjuvant postsurgical chemotherapy for colon adenocarcinoma who spontaneously developed nosocomial Pseudomonas meningitis causing severe trismus. The patient was initially admitted for ileus, developing neck stiffness and trismus on the thirteenth day of admission. Cerebrospinal fluid grew pansensitive Pseudomonas aeruginosa. Magnetic resonance imaging of the brain was consistent with bilateral subacute infarcts secondary to meningitis. The patient responded well to 21 days of broad spectrum antimicrobial therapy modified to ceftazidime alone following speciation and sensitivity. Outpatient follow-up at 46 days revealed normal maximal mouth opening with the ability to chew and tolerate a full diet. Trismus is a motor disturbance of the trigeminal nerve with difficulty in opening the mouth. Infectious etiologies commonly described include tetanus, odontogenic infections, or deep neck space infections. This is the first reported case of simultaneous nosocomial Pseudomonas meningitis and trismus in a patient with no history of neurosurgery or lumbar spinal manipulation.

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Section: Discussionmentioning

confidence: 70%

“…In the most recent literature, the term trismus has been applied generally to mean any condition in which mouth opening is inadequate [2]. While typical MMO range is between 40 and 60 mm, it is sex and age dependent.…”

Section: Introductionmentioning

confidence: 99%

Spontaneous NosocomialPseudomonas aeruginosaMeningitis Presenting as Trismus

Parr

Wheeler

Sharma

et al. 2017

Case Reports in Infectious Diseases

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“…For this study, we chose a MIO less than 36 mm as trismus in analogy with O'Leary [65]. Other trials have reported a wide range (6-86%) in the incidence of trismus in oral cancer patients [66,67].…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life in oral cancer survivors

Musa¹,

Mosleh²,

Shawky³

et al. 2015

Egyptian Journal of Oral & Maxillofacial Surgery

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Aim After surgery and radiation for the treatment of oral cancer, patients often develop oral complications such as speech, swallowing problems, and limited mouth opening. These problems may be caused by surgery and radiation. This study is a survey guided by a questionnaire for the post-treatment quality of life (QOL) in oral cancer patients in terms of the complications of cancer therapy. Patients and methodsThis study was carried out as a survey using the University of Washington Quality-of-Life Questionnaire aiming to identify different patterns of health-related QOL of patients with oral cancer. A total of 192 patients treated with surgery and/or radiation for oral cancer were interviewed. Maximal interincisal mouth opening was measured in these patients. ResultsPatients with tumors of posterior areas and patients with late stages showed a statistically significantly higher prevalence of limited mouth opening. Patients with limited mouth opening (trismus) showed a statistically significant lower mean score in the swallowing domain. The overall QOL questionnaire showed that the highest mean score was found with saliva (84.7), followed by taste (84.5). The lowest mean score was found with chewing (53.8), followed by swallowing (74.2). The overall mean QOL score was 75.9.Conclusion About half of the patients who underwent primary treatment for oral cancer developed trismus and reported problems with eating and speech. Chewing was identified as the poorest rating domain and presented the highest proportion of complaints in the sample of this study. Egypt J Oral Maxillofac Surg 6:81-95

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“…The pathophysiology of trismus depends on the cause11 (table 2). Neurological causes generally relate to involvement of the motor nucleus of the trigeminal nerve.…”

Section: Discussionmentioning

confidence: 99%

Trismus caused by paraneoplastic brainstem encephalitis

Malek

Damian²

2018

Pract Neurol

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We discuss the assessment and differential diagnoses of a middle-aged man who presented with trismus, double vision and behavioural problems. MRI scan of the brain was initially normal, but a month later showed high signal in the hippocampal region on fluid attenuated inversion recovery sequence (FLAIR) imaging. We suspected a paraneoplastic brainstem encephalitis because of his smoking history, rapidly progressive symptoms and abnormal brainstem signs. A positron emission tomography-CT scan identified abnormal subcarinal nodes, shown on biopsy to be metastatic small cell lung cancer. He is currently undergoing treatment with chemotherapy and radiotherapy.

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Trismus: Modern pathophysiological correlates

Cited by 18 publications

References 39 publications

Spontaneous NosocomialPseudomonas aeruginosaMeningitis Presenting as Trismus

Spontaneous NosocomialPseudomonas aeruginosaMeningitis Presenting as Trismus

Health-related quality of life in oral cancer survivors

Trismus caused by paraneoplastic brainstem encephalitis

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