Abstract:Abstract—Tris(2,3-dibromopropyl)isocyanurate (TBC or TDBP-TAZTO) is a new brominated flame retardant (BFR) used as a replacement of classic BFR, such as tetrabromobisphenol A. TBC is supposed to be safer than classic BFRs, but reports show that it may induce a similar toxic effect. Therefore, the aim of the present study was to determine the impact of TBC on the inflammation and activation of the apoptosis process in mouse cortical astrocytes in vitro. Our results have shown that TBC increases caspase-1 and ca… Show more
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