Triple Antithrombotic Therapy in Atrial Fibrillation Patients With an Indication for Oral Anticoagulation Undergoing Percutaneous Coronary Intervention

Abstract

DiscussionDr Picard: How common are patients like the one described and what are the therapeutic challenges for such patients undergoing PCI?Dr Asgar: Approximately 5% to 8% of patients undergoing PCI and stenting have an indication for long-term oral anticoagulation (OAC) because of AF. 7,8 Obviously, the main concern is to prevent death and disability for our patients. The challenge is finding the optimal balance between preventing thromboembolic events, such as thromboembolic stroke without increasing bleeding risk post-PCI. Chronic OAC is recommended in patients with AF and a CHA 2 DS 2 -VASc score ≥1, 4 and ≈30% of AF patients have concomitant CAD.