1997
DOI: 10.1507/endocrj.44.581
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Triphasic Changes in Thyroid Function in a Patient with Primary Hypothyroidism in the Course of Pregnancy and the Early Post-Partum Period.

Abstract: Abstract.We report a rare case of primary hypothyroidism in which thyroid function was changed from hypothyroidism to hyperthyroidism in the course of pregnancy and finally returned to hypothyroidism in the early post-partum period.She delivered an infant with neonatal Graves' thyrotoxicosis. Serum thyroid-stimulating antibodies (TSAb) and thyroid stimulating-blocking antibodies (TSBAb) coexisted in these patients.The triphasic changes in thyroid function may be explained by altered balance between TSAb and TS… Show more

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Cited by 3 publications
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“…4 The goals of maternal treatment are to maintain free thyroxine (T 4 ) at the upper level of the normal range with the minimal possible doses of antithyroid drugs. In fact, in about 30% of women antithyroid drugs may be discontinued in the last few weeks of pregnancy.…”
Section: Hyperthyroidism In Pregnancymentioning
confidence: 99%
“…4 The goals of maternal treatment are to maintain free thyroxine (T 4 ) at the upper level of the normal range with the minimal possible doses of antithyroid drugs. In fact, in about 30% of women antithyroid drugs may be discontinued in the last few weeks of pregnancy.…”
Section: Hyperthyroidism In Pregnancymentioning
confidence: 99%