Abstract:Drug reaction with eosinophilia and systemic symptoms (DRESS) is a delayed adverse drug reaction that is characterized by fever, cutaneous manifestation, enlarged lymph nodes, hematologic abnormalities, and organ involvement. Multiple medications have been reported to cause DRESS with the presentation varying from drug to drug. Some cases are mild and can be managed by stopping the causative agent along with supportive measures; however, other cases can lead to multi-organ failure requiring systemic corticoste… Show more
“…Patients should therefore be counselled to discontinue the drug should any rash develop and seek medical attention if it is severe or associated with mucositis. We recommend monitoring full blood count (FBC), renal function and liver function tests (LFTs) at baseline and after two to six weeks of therapy because trimethoprim can adversely affect renal and liver function 23 . Patients with reduced renal function, diabetes and those prescribed concomitant medications that can increase risk of hyperkalaemia should have ongoing monitoring 24 …”
Acne is a common skin condition that can have profound physical and psychological impacts. This article outlines its clinical presentation and recommended management in primary care and discusses when referral to secondary care is necessary.
“…Patients should therefore be counselled to discontinue the drug should any rash develop and seek medical attention if it is severe or associated with mucositis. We recommend monitoring full blood count (FBC), renal function and liver function tests (LFTs) at baseline and after two to six weeks of therapy because trimethoprim can adversely affect renal and liver function 23 . Patients with reduced renal function, diabetes and those prescribed concomitant medications that can increase risk of hyperkalaemia should have ongoing monitoring 24 …”
Acne is a common skin condition that can have profound physical and psychological impacts. This article outlines its clinical presentation and recommended management in primary care and discusses when referral to secondary care is necessary.
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