Trimethoprim/Sulfamethoxazole and Moxifloxacin Therapy for a Pediatric Stenotrophomonas Maltophilia Ventriculoperitoneal Shunt Infection

Abstract

Stenotrophomonas maltophilia is an increasingly prevalent cause of nosocomial infections. This report describes a 5-month-old male diagnosed with a S maltophilia ventriculoperitoneal shunt infection after a neurosurgical procedure. Intravenous trimethoprim/sulfamethoxazole and moxifloxacin successfully treated the patient. A literature review revealed a scarcity of similar reports, with none using moxifloxacin as an effective concomitant treatment with trimethoprim-sulfamethoxazole.

Stenotrophomonas maltophilia as a rare cause of meningitis and ventriculoperitoneal shunt infection

“…In addition to this we could identify five more cases of S. maltophilia meningitis [4, 6, 8, 9]. The age of the 35 previously reported patients ranged from preterm to 73 years with a M:F ratio of 24 : 11.…”

“…There were a total of 24 implants in these 22 patients. These include ten (42 %) EVD, nine (37 %) VP shunt, three (13 %) ommaya reservoir, one (4 %) aqueduct stent and one (4 %) aneurysm clip [1,[3][4][5][6][7][8][9]. Of the 35 cases reported six (17 %) patients succumbed to death.…”

“…We report a case of VP shunt infection and meningitis caused by S. maltophilia in a 24-year-old female who presented with VP shunt dysfunction and migration of the distal end of the shunt tube into the bowel. So far only 35 cases of S. maltophilia meningitis have been reported in the literature [1,[3][4][5][6][7][8][9]. The intention of this article is to present this rare case and to briefly review the relevant literature.…”

“…So far only 35 cases of S. maltophilia meningitis have been reported in the literature [1, 3–9]. The intention of this article is to present this rare case and to briefly review the relevant literature.…”