TRIM5 Promotes Systemic Lupus Erythematosus Through CD4(+) T Cells and Macrophage
Zhaobing Pan,
Qiaoshan Yang,
Xiaojing Zhang
et al.
Abstract:Purpose
Systemic lupus erythematosus (SLE) is a typical autoimmune disease characterized by the involvement of multiple organs and the production of antinuclear antibodies. This study aimed to investigate the molecular mechanism of SLE.
Patients and Methods
We retrieved genome-wide gene expression levels from five public datasets with relatively large sample sizes from the Gene Expression Omnibus (GEO), and we compared the expression profiles of peripheral blood mononuc… Show more
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