Triiodothyronine in Myxœdema Coma

Anderson, A. E.; Hausmann, Walther

doi:10.1016/s0140-6736(56)90370-1

Cited by 22 publications

(3 citation statements)

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“…Re-warming the patient leads to an increase in tissue metabolism and the heart may be incapable of meeting the extra demand. Anderson and Hausman (1956) noted the onset of angina with death in a pa-tient who had 50 micrograms of intravenous tri-iodothyronine in myxocdema coma. We did apply external warming but deliberately gave thyroid sicca rather than tri-iodothyronine as we did not wish to raise the metabolism too rapidly.…”

Section: Discussionmentioning

confidence: 99%

Hypopituitary Coma with Myocardial Infarction in a Patient with a Rathke Pouch Cyst

Mukerjee

Patel

1963

Int J Clinical Practice

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Section: Discussionmentioning

confidence: 99%

Hypopituitary Coma with Myocardial Infarction in a Patient with a Rathke Pouch Cyst

Mukerjee

Patel

1963

Int J Clinical Practice

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“…Haus-mann, andHemsted, 1953, 1955;-Summers, 1953 ;Malden, 1955;Karhausen and Zylberszac, 1955;Reid, 1955;Marshall and McCaughey, 1956;Dyson and Wood, 1956;Anderson and Hausmann, 1956). All these patients died except one in the series reported by Malden.…”

Section: Myxoedema Comamentioning

confidence: 95%

The Clinical Applications of Triiodothyronine

Goolden¹,

Burrell²

1957

BMJ

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“…Triiodothyronine has again been shown to be the treatment of choice in myxedema coma (186,187,188), although warnings against using even moderate doses intravenously have been voiced (189).…”

Section: Thyroidmentioning

confidence: 99%

Endocrinology

Asper¹,

Wilson²

1958

Annu. Rev. Med.

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Progress in endocrinology has been rapid. So large is the field that in one year's harvest an entire chapter could be devoted to each of the endo crine glands. Remarkable achievements have been in many instances be cause of the successful application of newer techniques such as chromatog raphy, radioisotope tracer procedures, and microchemical analyses. In this review an appraisal has been made of experimental work relating to the anterior pituitary, thyroid, adrenal cortex, parathyroid, and pancreas. ANTERIOR PITUITARYMuch interest has been shown in the hormones of the anterior pituitary. Variability of experimental data pertaining to these hormones has resulted, in large measure, from the use of impure preparations and, although im proved methods of purification have become available, they remain expen sive and laborious. Highly purifi ed hormones are now obtainable for re search purposes from the Endocrinology Section of the National Institutes of Health (1), and it seems likely that'their use will lead to a better appraisal of the specifi c action of these substances.For many years attempts have been made to ascribe specific hormonal functions to the various cells of the pituitary. At first there was only con jecture, but later assignation of function to specific cell types was based on histological examination of the pituitary in patients with various glandular disorders. More recently, special stains and solvents, bioassays, and selective destruction of minute parts of the pituitary have been applied to this analy sis. Many such studies have been performed and the definitive results of a recent project are outlined by Barrnett et al.(2 ). These workers show that thyrotropic, follicle-stimulating, and luteinizing hormones are localized to those basophiles which have an affinity for periodic acid-Schiff stain.Gro wth ho rmone (GH}.-It has been recognized that growth hormone from bovine or porcine sources is ineffective in man. Indeed, a degree of 'The survey of literature pertaining to this review was completed in August, 1957.For the sake of brevity the abbreviation et ai, is used when three or more authors' names appear on a paper. S The following abbreviations are used: GH (growth hormone); ACTH (adrenocorticotropin); MSH (melanocyte-stimulating hor;mone); TSH (thyroid stimulating hormone); FSH (follicle-stimulating hormone); LH (luteinizing hormone) : PBI (protein-bound iodine) : BMR (basal metabolic rate): TBP (thy roxine-binding protein) : PTH (parathyroid hormone ) : GFR (glomerular filtration rate): Tmp (maximal rate of tubular reabsorption of phosphorus by kidney): Tmo (maximal rate of tubular reabsorption of glucose by kidney).

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Triiodothyronine in Myxœdema Coma

Cited by 22 publications

References 0 publications

Hypopituitary Coma with Myocardial Infarction in a Patient with a Rathke Pouch Cyst

Hypopituitary Coma with Myocardial Infarction in a Patient with a Rathke Pouch Cyst

The Clinical Applications of Triiodothyronine

Endocrinology

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