Trigger factors in patients with a patent foramen ovale—associated stroke: A case-crossover study
Maikel HM Immens,
Merel S Ekker,
Esmee Verburgt
et al.
Abstract:Background: Patent foramen ovale (PFO) is a congenital anatomical variant which is associated with strokes in young adults. Contrary to vascular risk factors and atherosclerosis, a PFO is present from birth. However, it is completely unknown how an anatomical structure that is already present at birth in a large proportion of the population, can convert into a PFO that causes stroke in a few. Recent studies reported a significant association between certain trigger factors and ischemic stroke in young adults. … Show more
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