1999
DOI: 10.3171/jns.1999.90.2.0215
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Trigeminocardiac reflex during surgery in the cerebellopontine angle

Abstract: The authors' results show the possibility of occurrence of a TCR during manipulation of the central part of the trigeminal nerve when performing surgery in the CPA.

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Cited by 243 publications
(322 citation statements)
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References 44 publications
(74 reference statements)
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“…The high incidence (94%) of trigemino-cardiac reflex in our control cases is not new [2], but of the possible reasons put forward by Schaller et al to explain this incidence, only a few are actually applicable in our study (and those that were, were unavoidable). We ensured that our patients were not exposed to hypercarbia, hypoxia or light anesthesia by meticulously monitoring and maintaining SpO 2 and ETCO 2 within an acceptable range and by delivering 0.8% (nearly 1.3 MAC) inspired isoflurane.…”
Section: A Replymentioning
confidence: 53%
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“…The high incidence (94%) of trigemino-cardiac reflex in our control cases is not new [2], but of the possible reasons put forward by Schaller et al to explain this incidence, only a few are actually applicable in our study (and those that were, were unavoidable). We ensured that our patients were not exposed to hypercarbia, hypoxia or light anesthesia by meticulously monitoring and maintaining SpO 2 and ETCO 2 within an acceptable range and by delivering 0.8% (nearly 1.3 MAC) inspired isoflurane.…”
Section: A Replymentioning
confidence: 53%
“…Several pharmacological substances (e.g. gallamine, atropine) have been found already to more or less prevent the occurrence of this reflex during eye surgery [2,7], but no substance alone has completely suppressed it. A combination of intravenous atropine blocking the myocardial peripheral muscarinic receptor combined with retrobulbar xylocaine hydrochloride blocking conduction at the ciliary ganglion in the afferent limb of the trigemino-cardiac reflex, is effective in controlling it during eye surgery [8].…”
Section: A Replymentioning
confidence: 99%
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“…However, he claims to have previously seen a peripheral TCR in his own series [3]. As the TCR is now better known, we realize that not every bradycardia is a TCR [1] and that is why we publish only cases in which we have excluded hemodynamic changes not related to TCR by our own strict definition [5][6][7]. Regarding the case of the question of colleague Prabahakar, he speaks of a "sudden cardiac standstill" [2], but various differential diagnoses exist for a cardiac arrest during skin flap elevation.…”
mentioning
confidence: 99%
“…In 1999, Schaller et al were the first to describe the TCR during a neurosurgical procedure. Their series of cerebellopontine angle tumor operations had an 11% incidence of TCR upon manipulation of the trigeminal nerve near the brainstem [17]. More recently, severe TCR leading to asystole during transsphenoidal surgery of the pituitary has also been reported [7,18].…”
Section: Discussionmentioning
confidence: 99%