‘Trident sign’ in pelvis: sinister sign with poor prognosis

Gupta, Laxmikant; Yadav, Mukesh; Thulkar, Sanjay

doi:10.1136/bcr-2017-220460

Cited by 1 publication

(1 citation statement)

References 9 publications

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“…Additionally, Gupta et al noted the presence of a “trident sign” on contrast-enhanced CT and MRI of the lumbosacral region. This “trident sign” is associated with perineural cancer dissemination throughout the lumbosacral plexus, with diffuse thickening of the nerve plexus, and is predictive of adverse survival rates [ 73 ].…”

Section: Neurologic Consultationmentioning

confidence: 99%

Differentiating Lumbar Spinal Etiology from Peripheral Plexopathies

et al. 2023

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Clinicians have managed and treated lower back pain since the earliest days of practice. Historically, lower back pain and its accompanying symptoms of radiating leg pain and muscle weakness have been recognized to be due to any of the various lumbar spine pathologies that lead to the compression of the lumbar nerves at the root, the most common of which is the radiculopathy known as sciatica. More recently, however, with the increased rise in chronic diseases, the importance of differentially diagnosing a similarly presenting pathology, known as lumbosacral plexopathy, cannot be understated. Given the similar clinical presentation of lumbar spine pathologies and lumbosacral plexopathies, it can be difficult to differentiate these two diagnoses in the clinical setting. Resultingly, the inappropriate diagnosis of either pathology can result in ineffective clinical management. Thus, this review aims to aid in the clinical differentiation between lumbar spine pathology and lumbosacral plexopathy. Specifically, this paper delves into spine and plexus anatomy, delineates the clinical assessment of both pathologies, and highlights powerful diagnostic tools in the hopes of bolstering appropriate diagnosis and treatment. Lastly, this review will describe emerging treatment options for both pathologies in the preclinical and clinical realms, with a special emphasis on regenerative nerve therapies.

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Section: Neurologic Consultationmentioning

confidence: 99%