Tricuspid Valve Replacement After Cardiac Transplantation

Alharethi, Rami; Bader, Feras; Kfoury, Abdallah G.; Hammond, M. Elizabeth H.; Karwande, Shreekanth V.; Gilbert, E.M.; Doty, Donald B.; Hagan, Mary E.; Thomas, H.; Renlund, Dale G.

doi:10.1016/j.healun.2005.07.009

Cited by 26 publications

(16 citation statements)

References 38 publications

(62 reference statements)

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“…A flail leaflet was the cause of TVR in all but one of the patients. There were two mortalities in their series and improvement in symptoms was seen in 12 of the patients following surgery (23).…”

Section: Surgical Indications For Tricuspid Valve Repair or Replacementmentioning

confidence: 98%

Tricuspid valve regurgitation after heart transplantation

Kwon¹,

Shemin²

2017

Ann. Cardiothorac. Surg.

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Section: Surgical Indications For Tricuspid Valve Repair or Replacementmentioning

confidence: 98%

Tricuspid valve regurgitation after heart transplantation

Kwon¹,

Shemin²

2017

Ann. Cardiothorac. Surg.

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“…Alharethi et al [3 ] also recently reported their results of tricuspid valve replacement after cardiac transplantation, and this series is the largest reported to date. Amongst 871 orthotopic heart transplants at their institution between 1985 and 2004, 17 patients (2%) developed severe tricuspid regurgitation requiring surgical management.…”

Section: Recent Experience With Repairs and Replacementsmentioning

confidence: 71%

“…The series reported by Yankah et al [4] and more recently by Alharethi et al [3 ] provide further evidence to support the suspicion that damage to the chordae tendineae, resulting in a flail leaflet, is a common mechanism leading to severe symptomatic tricuspid regurgitation. Surgery to correct severe tricuspid valve regurgitation must take this mechanism into account.…”

Section: Repair or Replacement?mentioning

confidence: 80%

Tricuspid valve replacement after cardiac transplantation

Badiwala

2007

Current Opinion in Cardiology

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Results of tricuspid valve repair in the post-cardiac transplant setting are not ideal, and this strategy is better suited to treating functional tricuspid valve regurgitation resulting from annular dilatation. Tricuspid valve replacement with a bioprosthesis is a safe, durable, and effective method of treating tricuspid valve regurgitation following transplantation and allows for future endomyocardial biopsies to be performed. Mechanical valves should be avoided. A randomized controlled trial examining the long-term outcomes of prophylactic tricuspid annuloplasty is warranted.

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“…Due to a decline in donor numbers, the use of extended donor criteria has become more acceptable in clinical practice. This in turn leads to increasing the risk of developing cardiac pathology in the later clinical course after cardiac transplantation . Repeated cardiac surgery may be beneficial to restore allograft function and improve clinical outcome in transplant recipients .…”

Section: Introductionmentioning

confidence: 99%

Cardiac surgery in the heart transplant recipient: Outcome analysis and long‐term results

Farag

Arif

Raake

et al. 2019

Clinical Transplantation

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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. AbstractBackground: Survival rates following cardiac transplantation continue to improve.Due to the scarcity of available organs, extended donor criteria have become more prevalent in clinical practice. In this context, the risk of developing cardiac pathology requiring surgical correction is increasing. Methods: Between January 1991 and October 2010, a total of 479 patients received cardiac transplantations at the University Hospital Heidelberg. Of those, 18 (3.8%) patients required subsequent cardiac surgery until 2018. Short-and long-term analyses were performed. Results: Indications for cardiac surgery included valvular disease (n = 16) with the majority of cases affecting the tricuspid valve (n = 10), while 6 patients received mitral valve surgery, of whom 3 patients underwent concomitant valve surgery. Otherindications included CABG (n = 1) and re-transplantation (n = 1) for allograft dysfunction. Mean follow-up time was 6.5 years, while mean interval to surgery was 6.0 years. Early mortality was 11.1% (n = 2), while overall survival at 1, 5, and 10 years were, 88.1%, 81.4%, and 52.2%, respectively. Compared to an overall survival of that transplant cohort at 1, 5, and 10 years of 76.7%, 66.7%, and 52.4% percent, respectively (P = .271).Conclusion: According to our data, redo cardiac surgery can be performed with acceptable mortality and morbidity. Atrioventricular valve pathology plays a chief role in these patients. K E Y W O R D Sheart transplant, outcome analysis, repeat surgery

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Tricuspid Valve Replacement After Cardiac Transplantation

Cited by 26 publications

References 38 publications

Tricuspid valve regurgitation after heart transplantation

Tricuspid valve regurgitation after heart transplantation

Tricuspid valve replacement after cardiac transplantation

Cardiac surgery in the heart transplant recipient: Outcome analysis and long‐term results

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