A 448-Gb/s four-level pulse amplitude modulation (PAM4) free-space optical (FSO) communication through 600 m free-space link was constructed, utilizing polarization-multiplexing injection-locked vertical-cavity surface-emitting lasers (VCSELs) for presentation. When uniting fourwavelength polarization-multiplexing and PAM4 modulation schemes, the transmission capacity of FSO communications is substantially multiplied, with an aggregate transmission rate of 448 Gb/s [56 Gb/s PAM4/wavelength × 4 wavelengths × 2 polarizations (x-and y-polarizations)]. The results show that four 1.55 µm VCSEL transmitters with injection locking technique are sufficiently powerful for 448 Gb/s PAM4 signal transmission. Adopting a tunable optical band-pass filter and a polarization beam splitter for wavelength filtering and polarization de-multiplexing, the polarized wavelengths are effectually filtered and de-multiplexed in each polarized state. As the polarization state is well preserved in the scenario over 600 m free-space transmission, a sophisticated polarization tracker is not required in this proposed FSO communication. High bit error rate performance and accepted PAM4 eye diagrams are attained through 600 m free-space transmission. The four-wavelength polarization-multiplexing PAM4 FSO communication established here reveals the prominent benefits of high aggregate transmission capacity and long-distance free-space link.