Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu²⁺and pHin vitroandin vivo

Abstract

Polymer dots emitting in the red, green and blue color regions, have been successfully applied as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu2+ in HeLa cells and zebrafish.

Preparation and Applications of Carbon‐Based Fluorescent Nanothermometers

“…Thus, they have tunable optical and electrical properties. [ 39–46 ] Because of these outstanding characteristics, semiconducting polymers are spreadly used in the fields of photonics, sensing, solar energy conversion, and biomedicine. [ 39,40 ] In particular, semiconducting P‐dots represent an emerging nanotechnology in the fields of energy and health ( Figure ).…”

“…The resulting TE P‐dots with a single excitation at 365 nm, exhibited three‐color emission in the red, green, and blue regions, which is the same as the emission of the original single component ( Figure A). [ 45 ] Alifu et al. used an improved nanoprecipitation method to prepare functionalized P‐dots in aqueous solution.…”

“…Adapted with permission. [ 45 ] Copyright 2020, Royal Society of Chemistry. B) Synthesis and functionalization routine of P‐dots with efficient deep‐red emission at 650 nm.…”

“…They show the following advantages: high optical absorptivity, adjustable fluorescent emission, chemical stability, well biocompatibility, and low toxicity. [ 5–99 ] Given these superior properties, they have been extensively discussed in bioimaging devices, biosensors, catalysts, photovoltaic devices, as well as fluorescent nanothermometers for spatially resolved temperature ( Figure ). [ …”

19F-Grafted Fluorescent Carbonized Polymer Dots for Dual-Mode Imaging

“…Carbon dots (CDs) have been studied extensively due to their unique properties such as excellent photostability, − low cytotoxicity, − ease of preparation, , and low cost. − As a type of CD, polymer dots (PDs) , with a low carbonization degree are regarded as a transition structure between nonconjugated polymer nanoparticles and fully carbonized CDs. PDs normally possess excellent biocompatibility with rich functional moieties at the edge sites.…”