Trichosporon inkin, an unusual agent of fungal sinusitis: A report from south India

Abstract

The aetiology of fungal sinusitis is diverse and changing. Aspergillus species has been the most common cause for fungal sinusitis, especially in dry and hot regions like India. Trichosporon species as a cause for fungal sinusitis has been very rarely reported the world over. Here, we report a rare case of allergic fungal sinusitis caused by Trichosporon inkin in a 28-year-old immunocompetent woman. Bilateral nasal obstruction, nasal discharge and loss of smell were her presenting complaints. Diagnostic nasal endoscopy showed bilateral multiple polyps. Functional endoscopic sinus surgery was performed and many polyps were removed. Based on mycological and histopathological studies, the pathogen was identified as T. inkin.

Molecular characterisation and antifungal susceptibility of clinical Trichosporon isolates in India

“…A case of white piedra of scalp due to T. inkin was earlier reported from our centre . Literature search revealed that two cases of white piedra and a case of fungal rhinosinusitis due to T. inkin have been reported from India . Isolation of this species from blood has never been reported before.…”

Identification of three yeast species using the conventional and internal transcribed spacer region sequencing methods as first or second global record from human superficial infections

“…They have been involved in a variety of opportunistic infections and have been recognised as emerging fungal pathogens in immunocompromised hosts . Studies also indicated that T. asahii , T. asteroids , T. cutaneum , T. faecale , T. inkin , T. mucoides or T. ovoides are involved in hypersensitivity pneumonitis, pulmonary infections and superficial infections, sinusitis, fungaemia, in HIV patients, a bone marrow transplant recipient, a solid organ transplant recipient and in a patient with severe aplastic anaemia . Members of the genus Trichosporon have occasionally been implicated as nail pathogens and in subcutaneous infections .…”

Unusual causes of fungal rhinosinusitis: A study from a tertiary care centre in South India

“…[15] Janagond et al reported a case of rhinosinusitis caused by Trichosporon inkin from South India. [7] Shivaprakash et al reported a case of AFRS caused by Neosartorya hiratsukae for the fi rst time from India. [16] In our study, we found unusual causes of fungi causing rhinosinusitis in 4 (26.67%) out of the 15 culture positive cases of FRS.…”