Trichosporon asahii causing subcutaneous mycoses in an immunocompetent patient: case report and a minireview

A Rare Case of a Retroperitoneal Abscess Due to Trichosporon spp. in an Immunocompetent Patient

“…Trichosporon spp. is known to be a commensal organism of the digestive tract and can colonize the skin of healthy patients [8]. Although it is usually associated with infections in immunocompromised patients, there are reported cases of infections in immunocompetent individuals, especially after surgical interventions, as seen in our patient.…”

“…Unfortunately, the treatment of trichosporonosis remains a challenge because few studies have been dedicated to evaluating the in vitro and in vivo activities of different antifungals against clinically relevant Trichosporon species [4]. Nevertheless, the literature indicates that azoles, except for fluconazole, have good activities against Trichosporon species, while amphotericin B shows limited in vitro and in vivo activity against these microorganisms [8]. Our patient improved significantly under voriconazole, which has demonstrated superior in vitro activities against Trichosporon species compared to amphotericin B or fluconazole [14][15][16].…”