Trichophyton tonsurans – ein Emerging-Pathogen im Ringsport in Deutschland

Schießl, Jasmin; Uhrlaß, Silke; Wichmann, Kathrein; Wilde, D.; Krüger, Constanze; Nenoff, P.

doi:10.1007/s00105-021-04803-7

Cited by 10 publications

(11 citation statements)

References 36 publications

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“…A number of studies have shown that T. tonsurans is widely distributed in contact sports, particularly martial arts 19,26,29–33 . However, in this study only 4 of 23 patients practiced martial arts and only 1 person practiced another contact sport.…”

Section: Discussionmentioning

confidence: 53%

“…A number of studies have shown that T. tonsurans is widely distributed in contact sports, particularly martial arts. 19,26,[29][30][31][32][33] However, in this study only 4 of 23 patients practiced martial arts and only 1 person practiced another contact sport. The data therefore highlight that T. tonsurans is not limited to outbreaks in contact sports but more widely distributed in the general population.…”

Section: Ta B L Ementioning

confidence: 99%

“…It has also been linked to outbreaks in other areas with social interaction, like kindergartens, schools and workplaces 21–24 . In Germany, however, T. tonsurans has thus far only played a minor role in tinea corporis and tinea capitis , 1,13 with only a few local outbreaks being described 25–28 …”

Section: Introductionmentioning

confidence: 99%

“…[21][22][23][24] In Germany, however, T. tonsurans has thus far only played a minor role in tinea corporis and tinea capitis, 1,13 with only a few local outbreaks being described. [25][26][27][28] This study aims to determine the proportion of T. tonsurans culture-positive patients relative to all dermatophyte culture-positive patients in the dermatology department of a large university hospital in Germany from 2019 to 2022. Furthermore, the affected patient population and disease patterns are thoroughly characterised.…”

Section: Introductionmentioning

confidence: 99%

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Increasing incidence of Trichophyton tonsurans in Munich—A single‐centre observation

Pilz

Köberle

Kain

et al. 2023

Mycoses

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Background: Tinea capitis and tinea corporis are highly prevalent fungal skin infections, which globally are mainly caused by Microsporum canis and Trichophyton rubrum, respectively. While in the United States and Great Britain Trichophyton tonsurans is widely prevalent as a causative pathogen, it so far only plays a minor role in Germany. Objectives: Since the frequency of pathogenic species varies regionally and temporally, this study assesses the proportion of Trichophyton tonsurans infections in the dermatology department of a large university hospital in Germany from 2019 to 2022 and thoroughly characterises the affected patient population. Patients/Methods: This retrospective study at the Technical University of Munich analyses mycological culture results regarding the identified dermatophyte and infection site. Detailed patient and disease-related information on Trichophyton tonsurans positive patients was obtained. Results: In 2022, 23 patients of 111 dermatophyte culture-positive patients tested positive for Trichophyton tonsurans. This accounted for 20.7% and represented a tenfold increase from 2.1% in 2019. Contact sports were only practiced by 21.7% of patients, and no common hotspot or other linkage could be identified between the cases. Additionally, 47.8% of the patients received a systemic treatment, with 30.4% visiting the clinic more than three times. In 2022, 21.7% were diagnosed with a simultaneous infection of the capillitium and body, whereas this was only observed in 7.1% of cases in 2019 to 2021. Conclusions: This study suggests an increase of Trichophyton tonsurans infections via several routes of transmission.

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Section: Discussionmentioning

confidence: 53%

Section: Ta B L Ementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Increasing incidence of Trichophyton tonsurans in Munich—A single‐centre observation

Pilz

Köberle

Kain

et al. 2023

Mycoses

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“…reported worldwide, include the USA [15,16], France [17], Mexico[18], Iran [19], Japan [3], Germany [20],…”

Section: Discussionmentioning

confidence: 99%

Clonal Outbreak of Trichophyton tonsurans Causing Tinea Capitis Among a Wrestling Team in Beijing, China

et al. 2022

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Trichophyton tonsurans, an anthropophilic dermatophyte, mostly causes tinea capitis and tinea corporis and often associates with outbreaks among athletes involving in combat sports. Here, we report an outbreak of tinea capitis caused by T. tonsurans among ve juvenile athletes aged ten to fourteen in a wrestling team in Beijing, China. Scrapings from the lesions of the ve patients were performed by direct microscopic examination and fungal culture. The fungal pathogens were all identi ed as T. tonsurans by morphology and sequencing of the internal transcribed spacer (ITS) regions. Multilocus genotyping analysis was performed by sequencing of the ve gene loci including the ITS and non-transcribed spacer (NTS) of the ribosomal RNA (rRNA) locus, alkalineprotease-1 (ALP1), metalloprotease-5 (MEP5), carboxypeptidases Y (CarbY). The sequences of these markers were identical among the ve isolates, revealing a single genotype. Antifungal susceptibilities of terbina ne (TBF), itraconazole (ITC), uconazole (FLC), ketoconazole (KTC), and amphotericin B (AMB) against T. tonsurans was determined by broth microdilution method according to the Clinical and Laboratory Standards Institute (CLSI) M38-A3 document and the minimum inhibitory concentrations (MICs) were 0.015 µg/mL, 0.015 µg/mL, 8 µg/mL, 0.06 µg/mL, and 0.5 µg/mL, respectively. In conclusion, we report an outbreak of tinea capitis caused by T. tonsurans among wrestlers in Beijing, China. Multilocus genotyping analysis revealed that all isolates consisted of a single genotype, suggesting the outbreak may be caused by a single strain of T. tonsurans. The isolates were all susceptible to the common antifungal drugs treating tinea capitis.

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Terbinafin-resistente Dermatophytosen und Onychomykose durch Trichophyton rubrum

Appelt

Nenoff²,

Uhrlaß³

et al. 2021

Hautarzt

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Trichophyton tonsurans – ein Emerging-Pathogen im Ringsport in Deutschland

Cited by 10 publications

References 36 publications

Increasing incidence of Trichophyton tonsurans in Munich—A single‐centre observation

Increasing incidence of Trichophyton tonsurans in Munich—A single‐centre observation

Clonal Outbreak of Trichophyton tonsurans Causing Tinea Capitis Among a Wrestling Team in Beijing, China

Terbinafin-resistente Dermatophytosen und Onychomykose durch Trichophyton rubrum

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