Trichofolliculoma presenting as lobulated Mass: A rare presentation

Abstract

Trichofolliculoma represents abortive differentiation of pluripotent skin cells toward hair follicles. We present a case of an adult female with lobulated mass involving the tip and dorsum of the nose for the last 15 years. The systemic and radiological examinations were noncontributory. The clinical diagnosis was thought to be dermoid cyst. The fine-needle aspiration cytology of the lobulated mass was performed, and the cytology smears showed anucleate squames admixed with sebaceous cells. The possibility of a benign skin adnexal lesion was suggested. The biopsy was done, and the final diagnosis of trichofolliculoma was made. The wide local excision of the mass was performed, and no recurrence was noted during the follow-up of 1 year.

SkIndia Quiz 41: Asymptomatic skin‑colored papule on the scalp skin

“…Trichofolliculoma is a rare pilar tumor and intermediate in differentiation between a hair follicle nevus, which is simple hyperplasia of the hair follicle, and a trichoepithelioma, which lacks maturation of the hair follicle. [ 1 ]…”

“…It usually presents as a solitary nodule approximately 0.5 cm in diameter in the head and neck region with central umbilication and a tuft of fine hairs protruding from it. [ 1 2 ] Trichofolliculoma is mostly seen in the head and neck regions. [ 1 ] Although the exact etiology of trichofolliculoma remains unknown, it is considered to represent immature differentiation of pluripotent skin cells toward hair follicles.…”

“…[ 1 2 ] Trichofolliculoma is mostly seen in the head and neck regions. [ 1 ] Although the exact etiology of trichofolliculoma remains unknown, it is considered to represent immature differentiation of pluripotent skin cells toward hair follicles. [ 2 ] Trichofolliculoma clinically presents as small-sized lesions ranging between 0.2.0.5 cm in diameter, which are often whitish-red pearly papules.…”

“…A tuft of white vellus hairs yields a distinctive morphological appearance to trichofolliculoma. [ 1 ] Trichofolliculoma may affect individuals of any age, but it is mostly seen in adults. [ 2 ] It is not associated with family history or other systemic diseases and is not a component of a syndrome.…”

Trichofolliculoma of the nasal vestibule

“…При гистологическом исследовании фрагмента ткани опухоли был обнаружен страти фицированный сквамозный эпителий с фрагмента ми волосяных стержней и волосяные фолликулы различной степени зрелости. На основании полу ченных результатов была диагностирована трихо фолликулома и выполнено широкое иссечение опухоли без признаков рецидива в течение 1 года наблюдения [14].…”