Trichinella spiralis infection and transplacental passage in human pregnancy

Saracino, María P.; Calcagno, Marcela A.; Beauche, Emilia Bilen; Garnier, Ariel; Vila, Cecilia C.; Granchetti, Hugo; Taus, María Rosalba; Venturiello, Stella M.

doi:10.1016/j.vetpar.2016.06.019

Cited by 7 publications

(2 citation statements)

References 37 publications

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“…has rarely been investigated. A study on six pregnant women suggests that transplacental passage of new-born larvae is possible [ 51 ]. A case report from The Slovak Republic confirmed Trichinella larvae that infected the foetus in the early stage of development [ 52 ].…”

Section: Discussionmentioning

confidence: 99%

Retrospective Survey of Human Trichinellosis in a Romanian Infectious Diseases Hospital over a Thirty-Year Interval—The Never-Ending Story

Lupşe

Ionică²,

Flonta³

et al. 2023

Pathogens

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Trichinellosis remains a food-safety risk in Romania due to cultural traditions and food behavior. The aim of the present study was to evaluate the epidemiological, clinical and therapeutical data of all human trichinellosis cases in patients admitted to an Infectious Diseases Hospital from northwestern Romania during a thirty-year interval. Between 1 January 1988 and 31 December 2018, a total of 558 patients were hospitalized with the diagnosis of trichinellosis. The number of cases/year varied between 1 and 86. The source of infection was known for 524 patients, represented by domestic pig meat (n = 484; 92.37%) and wild boar (n = 40; 7.63%). Most patients (410; 73.48%) presented were part of family or group outbreaks. Demographical and clinical data of patients will be presented. Antiparasitic therapy was prescribed in 99.46% of cases, and corticosteroids were prescribed in 77.06% of patients. In total, 48 patients (8.6%) presented complications of trichinellosis: 44 for a single complication (neurological, cardiovascular or respiratory); the others multiple complications. Pregnancy was documented in five patients. No fatalities occurred during the study period. Although the number of hospitalized patients has decreased in the last years, trichinellosis still remains an important public health problem in northwestern Romania.

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Section: Discussionmentioning

confidence: 99%

Retrospective Survey of Human Trichinellosis in a Romanian Infectious Diseases Hospital over a Thirty-Year Interval—The Never-Ending Story

Lupşe

Ionică²,

Flonta³

et al. 2023

Pathogens

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“…recognize a single host in which two generations of the parasite can occur but it does not involve a free-living stage [5,6]. The life cycle consists of three phases: intestinal, migrant, and muscular [7]. In the muscular phase, the larvae can survive from about 1–2 to 10–15 years in hosts because they form a nurse cell–parasite complex into myocytes after de-differentiation and re-differentiation of muscle cells [8,9].…”

Section: Introductionmentioning

confidence: 99%

Accreditation Procedure for Trichinella spp. Detection in Slaughterhouses: The Experience of an Internal Laboratory in Italy

Schirone

Visciano

Olivastri³

et al. 2019

Foods

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Trichinellosis is a severe foodborne zoonotic disease due to the consumption of undercooked meat containing Trichinella spp. larvae. According to Commission Regulation (EU) No 1375/2015, domestic pigs, farmed wild boar, and horses must be tested for the presence of the parasite in the muscles as part of post-mortem examination. In this study, the accreditation procedure and the maintenance of the certificate for internal laboratory attached to a slaughterhouse are described. The main advantages of such accreditation are represented by the possibility to obtain fast results in order to process carcasses quickly, whereas the difficulties for the technician are linked to performing proficiency testing and following training courses. This program can be considered particularly useful for surveillance and food safety purposes.

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Studies on vertical transmission of Trichinella spiralis in experimentally infected guinea pigs (Cavia porcellus)

et al. 2017

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An experimental study to enhance knowledge on the capability of Trichenella spiralis to pass from guinea pigs to progeny at different periods of pregnancy or lactation was performed. For this purpose, 18 female adult guinea pigs were inoculated with 100 or 1000 T. spiralis muscle larvae (ML) during early, late gestation and during lactation period. The presence of T. spiralis (ML) in mothers and newborns was studied through enzymatic digestion from muscle samples. ML were observed in 9 of 42 newborn guinea pigs and levels of infection were significantly higher when infections of mothers were done during late gestation (p = 0.0046) with the high infective dose (p = 0.0043). T. spiralis ML were not recovered from any of the newborns from mothers infected in the lactation period. Ten out of 18 infected mothers presented larvae 1 in their mammary glands. Muscle samples from the tongue and the masseter showed the highest larval burdens. These observations confirm previous reports on that ML of T. spiralis are capable to pass through placental tissues to reach and encyst in striated muscle groups of newborn guinea pigs. This study may also reinforce the importance of preventive programs to control trichinellosis in those endemic areas where pregnant women would have high risk of infection.

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Trichinella spiralis infection and transplacental passage in human pregnancy

Cited by 7 publications

References 37 publications

Retrospective Survey of Human Trichinellosis in a Romanian Infectious Diseases Hospital over a Thirty-Year Interval—The Never-Ending Story

Retrospective Survey of Human Trichinellosis in a Romanian Infectious Diseases Hospital over a Thirty-Year Interval—The Never-Ending Story

Accreditation Procedure for Trichinella spp. Detection in Slaughterhouses: The Experience of an Internal Laboratory in Italy

Studies on vertical transmission of Trichinella spiralis in experimentally infected guinea pigs (Cavia porcellus)

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