Triamcinolone acetonide and hexacetonide intra-articular treatment of symmetrical joints in juvenile idiopathic arthritis: a double-blind trial

Abstract

Even when TA is given at higher doses, TH is more effective and should be considered the drug of choice for intra-articular treatment of JIA.

EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)

“…108 109 Among the intra-articular corticosteroids, there is some indication that triamcinolone hexacetonide is the most effective. 110 In summary, systemic glucocorticoids-either alone or as part of a DMARD combination strategy-are effective in the short term relief of signs and symptoms, and are probably effective in retarding radiographic progression in early and established rheumatoid arthritis. The systemic use of glucocorticoids in early arthritis has not yet been formally investigated.…”

Juvenile idiopathic arthritis and rheumatoid arthritis: bacterial diversity in temporomandibular joint synovial fluid in comparison with immunological and clinical findings

“…Systemic glucocorticoids are not routinely recommended for treatment of JIA. The recommended steroid is triamcinolone hexacetonide, and expected improvement should last for at least 4 months (Zulian et al 2004). …”

Modern management of juvenile idiopathic arthritis

“…The agent of choice is triamcinolone hexacetonide, which is longer acting than alternative preparations, with mean duration of response just over 12 months. 20,21 Joint injections are used frequently for the treatment of oligoarticular disease, where they may suffice as monotherapy, thus sparing the need for regular systemic medication. They may also be used for children whose disease has a polyarticular course, to 'mop up' residual or flaring joints in children who have had an otherwise good response to systemic therapies.…”