Trends Over Time in Antipsychotic Initiation at a Large Children's Health Care System

First do no harm: use off-label antipsychotic medication in children and adolescents with great caution

“…In France, second-generation antipsychotic dispensing rates increased from 2.7 to 3.4 per 1,000 children and adolescents from 2006 to 2013. In contrast, according to US Medicaid prescription data, pediatric antipsychotic orders decreased from 54.9 prescriptions per 10,000 person months in the first quarter of 2013 to 34.1 per 10,000 person months in the last quarter of 2017 [6]. Also, antipsychotic prescriptions in Germany in children younger than 6 years decreased from 2.42 per 1000 subjects in 2004 to 0.48 in 2011 [7].…”