Trends of the incidence of drug use disorders from 1990 to 2017: an analysis based on the Global Burden of Disease 2017 data

Abstract

Aim Drug use disorders are an important issue worldwide. Systematic attempts to estimate the global incidence of drug use disorders are rare. We aimed to determine the incidence of drug use disorders and their trends. Methods We obtained the annual incident cases and age-standardised incidence rate (ASR) of drug use disorders from 1990 to 2017 using the Global Health Data Exchange query tool. The estimated annual percentage changes of the ASR were used to quantify and evaluate the trends in the incidence rate. Gaussian process regression and the Pearson's correlation coefficient were used to assess the relationship between the ASR and socio-demographic index (SDI). Results The number of drug use disorders’ cases increased by 33.5% from 1990 to 2017 globally, whereas the ASR exhibited a stable trend. The ASR was higher in men than in women. Most cases (53.1%) of drug use disorders involved opioid. A positive association (ρ=0.35, p < 0.001) was found between ASR and SDI. Teenagers aged 15–19 years had the highest incidence rate. Conclusions The incident cases of drug use disorders were increasing, but the incidence rate did not change significantly from 1990 to 2017. Current preventive measures and policies for drug use disorders might have little effect. The present results suggest that future strategies should focus on men, teenagers and high-risk regions in order to improve the current status of drug use disorders.

Ageing and older people who use illicit opioids, cocaine or methamphetamine: a scoping review and literature map

“…That this population has grown is undisputed in the literature [8,23,30]. However, it is unclear to what extent evolving incidence rates of illicit drug use and overdose epidemics will impact upon mortality rates and the prevalence of drug use among older people in future [105][106][107]. There is a need to develop shared theories and frameworks and improve methodological rigour; clearly define and characterize the population of interest; shift from description to explanation; collect data on particularly marginalized older PWUD (e.g.…”

Trends of the Global Burden of Disease Attributable to Cannabis Use Disorder in 204 Countries and Territories, 1990–2019: Results from the Disease Burden Study 2019

“…The introduction of DSM-V by the American Psychiatric Association included a shift from DSM-IV abuse and dependence to a category of use disorder, defined as mild, moderate, and severe in severity. Moderate to severe substance use disorders in DSM-V may be higher than DSM-IV and ICD-10 dependence, which means that if DSM-V prevalence estimates are used, the estimated burden of substance use disorders may be higher (Pan et al, 2020 ). Fourth, more and more evidence showed that there is a causal relationship between cannabis use and traffic accidents, and whether accidental injuries are included in the disease burden of CUD is still controversial.…”

“…From 1990 to 2019, the burden of substance use disorders has increased, including alcohol, amphetamines, cannabis, and cocaine as substance use disorders (Degenhardt et al, 2018 ; Pan et al, 2020 ; Whiteford et al, 2013 ). In this research, we analyzed data from the 2019 Global Burden of Disease Study (GBD) to estimate the incidence and prevalence of CUD and calculated the disease burden of CUD in 204 countries and territories and 21 regions over the past three decades.…”

Cognitive network reconstruction in individuals who use opioids compared to those who do not: Topological analysis of cognitive function through graph model and centrality measures

“…This increase has occurred mostly in the regions with low, low-middle and middle socio-demographic index. Meanwhile, opioid use disorder (OUD) accounted for most of the cases with its proportion increasing from 47.18% in 1990 to 53.1% in 2017 ( 2 ), and continues to account for the largest burden of disease attributed to drug use ( 1 ).…”