Trends of allergic symptoms in school children: large‐scale long‐term consecutive cross‐sectional studies in Osaka Prefecture, Japan

Yura, Akiko; Kouda, Katsuyasu; Iki, Masayuki; Shimizu, Tadahiko

doi:10.1111/j.1399-3038.2011.01159.x

Cited by 26 publications

(35 citation statements)

References 29 publications

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“…Yura and Shimizu conducted a questionnaire survey of health symptoms in four million school children (aged 7-12 years) in Osaka and reported that the lifetime prevalence of AD increased from 15.0% in 1985 to 24.1% in 1993 but leveled off thereafter (22.9% in both 1995 and 1997) [18]. Their subsequent study also confirmed the consecutive decrease of AD prevalence from 1993 to 2006 (16.5%) [19]. Meanwhile, the prevalence of wheezing was constant at 3.0 ± 0.1% between 1975 and 1983, and then increased to 4.7% in 1993.…”

Section: Introductionmentioning

confidence: 89%

Current status of atopic dermatitis in Japan

Furue

Chiba

Takeuchi

2011

Asia Pacific Allergy

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Atopic dermatitis (AD) is a common, chronic or chronically relapsing, severely pruritic, eczematous skin disease. AD is the second most frequently observed skin disease in dermatology clinics in Japan. Prevalence of childhood AD is 12-13% in mainland Japan; however, it is only half that (about 6%) in children from Ishigaki Island, Okinawa. Topical steroids and tacrolimus are the mainstay of treatment. However, the adverse effects and emotional fear of long-term use of topical steroids have induced a "topical steroid phobia" in patients throughout the world. Undertreatment can exacerbate facial/periocular lesions and lead to the development of atopic cataract and retinal detachment due to repeated scratching/rubbing/patting. Overcoming topical steroid phobia is a key issue for the successful treatment of AD through education, understanding and cooperation of patients and their guardians.

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Section: Introductionmentioning

confidence: 89%

Current status of atopic dermatitis in Japan

Furue

Chiba

Takeuchi

2011

Asia Pacific Allergy

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“…One study of Japanese elementary schoolchildren showed that the lifetime prevalence of eczema increased from 15.3% in 1985 to 24.2% in 1993 before decreasing to 16.5% in 2006, while the prevalence of rhinitis increased from 11.6% in 1983 to 24.7% in 2006 [2]. …”

Section: Introductionmentioning

confidence: 99%

Polyunsaturated fatty acid intake and prevalence of eczema and rhinoconjunctivitis in Japanese children: The Ryukyus Child Health Study

et al. 2011

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BackgroundThe recent increase in the prevalence of allergic disorders might be a consequence of increased intake of n-6 polyunsaturated fatty acids (PUFAs) and reduced intake of n-3 PUFAs. The current cross-sectional study examined the association between intake levels and the prevalence of eczema and rhinoconjunctivitis in Japanese children.MethodsSubjects were 23,388 schoolchildren aged 6-15 years residing in Okinawa. The presence of eczema and/or rhinoconjunctivitis was determined according to the criteria of the International Study of Asthma and Allergies in Childhood. A brief diet history questionnaire for children and adolescents was administered to acquire information on dietary factors. Adjustment was made for age, sex, residential municipality, number of siblings, smoking in the household, body mass index, paternal and maternal history of allergic diseases, and paternal and maternal educational level.ResultsThe prevalences of eczema and rhinoconjunctivitis in the previous 12 months were 7.0% and 8.0%, respectively. Consumption of PUFAs, n-3 PUFAs, α-linolenic acid, n-6 PUFAs, and linoleic acid was positively associated with the prevalence of eczema: the adjusted odds ratios (ORs) between extreme quintiles (95% confidence intervals [CIs], P for trend) were 1.26 (1.07-1.48, 0.04), 1.31 (1.11-1.54, 0.009), 1.31 (1.12-1.55, 0.003), 1.26 (1.07-1.48, 0.01), and 1.27 (1.08-1.49, 0.01), respectively. Arachidonic acid intake was independently inversely related to eczema: the adjusted OR between extreme quintiles was 0.81 (0.69-0.95, 0.0008). Eczema was not associated with eicosapentaenoic or docosahexaenoic acid intake, or with the ratio of n-3 to n-6 PUFA intake. Only arachidonic acid intake was statistically significantly related to the prevalence of rhinoconjunctivitis, showing a clear inverse linear trend: the adjusted OR between extreme quintiles was 0.86 (0.74-0.997, 0.03).ConclusionsConsumption of n-3 and n-6 PUFAs, especially α-linolenic acid and linoleic acid, may be positively associated with eczema. Arachidonic acid intake may be inversely related to eczema and rhinoconjunctivitis.

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“…Environmental factors associated with industrialization likely play a role [ 51 ] . In high prevalence areas of Europe and Asia, this increase appears to be stabilizing at approximately 20% [ 81,85 ] .…”

Section: Prevalencementioning

confidence: 82%

Update on Atopic Eczema with Special Focus on Dryness and the Impact of Moisturizers

Simpson

2012

Treatment of Dry Skin Syndrome

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Trends of allergic symptoms in school children: large‐scale long‐term consecutive cross‐sectional studies in Osaka Prefecture, Japan

Cited by 26 publications

References 29 publications

Current status of atopic dermatitis in Japan

Current status of atopic dermatitis in Japan

Polyunsaturated fatty acid intake and prevalence of eczema and rhinoconjunctivitis in Japanese children: The Ryukyus Child Health Study

Update on Atopic Eczema with Special Focus on Dryness and the Impact of Moisturizers

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