Trends in US Kidney Transplantation During the COVID-19 Pandemic

Bordes, Stephen J; Montorfano, Lisandro; West-Ortiz, Wesley; Valera, Roberto J.; Cracco, Alejandro; Alonso, Mileydis; Pinna, Antonio; Ebaid, Samer

doi:10.7759/cureus.12075

Cited by 10 publications

(13 citation statements)

References 23 publications

(30 reference statements)

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“…One year into the pandemic, there is no evidence of the predicted post-pandemic surge in listings that could strain transplant system resources, although transplant volumes have returned to pre-pandemic levels. 13 Beyond the size of the waitlist, however, the pandemic may be having impacts on the composition of the kidney waiting list. In particular, demographic groups that have experienced the greatest waitlist mortality during the pandemic, including candidates older than 50 years, candidates with diabetes, and Hispanic candidates, are also the groups that have been growing steadily in their relative proportion of the waiting list during the past decade.…”

Section: Discussionmentioning

confidence: 99%

Impact of COVID‐19 pandemic on the size of US transplant waiting lists

Miller

Wey

Hart

et al. 2022

Clinical Transplantation

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Background More patients are waitlisted for solid organs than transplants are performed each year. The COVID‐19 pandemic immediately increased waitlist mortality and decreased transplants and listings. Methods To calculate the number of candidate listings after the pandemic began and short‐term changes that may affect waiting time, we conducted a Scientific Registry of Transplant Recipients surveillance study from January 1, 2012 to February 28, 2021. Results The number of candidates on the liver waitlist continued a steady decline that began before the pandemic. Numbers of candidates on the kidney, heart, and lung waitlists decreased dramatically. More than 3000 fewer candidates were awaiting a kidney transplant on March 7, 2021, than on March 8, 2020. Listings and removals decreased for each solid organ beginning in March 2020. The number of heart and lung listings returned to equal or above that of removals. Listings for kidney transplant, which is often less urgent than heart and lung transplant, remain below numbers of removals. Removals due to transplant decreased for all organs, while removals due to death increased for only kidneys. Conclusions We found no evidence of the predicted surge in listings for solid organ transplant with a plateau or control of the pandemic.

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Section: Discussionmentioning

confidence: 99%

Impact of COVID‐19 pandemic on the size of US transplant waiting lists

Miller

Wey

Hart

et al. 2022

Clinical Transplantation

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“…The pandemic has not only disrupted kidney transplant patients but has also influenced transplantation systems, donation chains, and timely and secure transplant surgeries [9] . As the SARS-CoV-2 virus outbreak progresses, transplantation centers meet various difficulties that have pressured a steep decline in kidney transplants, including living or deceased donor transplants [10] .…”

Section: Discussionmentioning

confidence: 99%

“…Unfortunately, those who continue on the waiting list need kidney replacement treatment. For these patients, 3 times per week, hemodialysis is the mainstay of end-stage kidney disease therapy [9] . These patients remain indoors for 4 hours in frequent contact with other patients and health care staff, increasing their risk of acquiring SARS-CoV-2.…”

Section: Discussionmentioning

confidence: 99%

Global Effects of SARS-CoV-2 Era on Kidney Transplantation Activities: Analysis of WHO Data

Ferhatoğlu

Filiz

Şahin

et al. 2022

Transplantation Proceedings

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Background Uncertainty raises questions in kidney transplant during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic regarding the recipient, the donor, and health care professionals. The pandemic not only has disrupted kidney transplanted patients but also has influenced transplant systems, donation chains, and timely and safe transplant surgeries. In the present study, we aimed to explore the global effects of the SARS-CoV-2 pandemic on kidney transplant. Methods We collected transplantation statistics and SARS-CoV-2 pandemic data from the World Health Organization website on June 15, 2021. Spearman correlation analysis was applied to assess the strength of a monotonic relationship among quantitative variables. We also demonstrated the clinical characteristics of our kidney recipients with SARS-CoV-2 infection. Results Comparison of the mean of global kidney transplantation statistics between 2010 and 2019 with 2020 statistics showed a significant decrease in kidney transplant from living donors ( P < .001). From the beginning of the pandemic to June 15, 2021, 1 of the 43 kidney transplant patients we treated in our clinic died of SARS-CoV-2 infection after discharge. Two of the patients we transplanted and saw in follow-up before the pandemic died of SARS-CoV-2 infection. Conclusion While the overall kidney transplant numbers have increased in the year to date, kidney transplants decreased drastically at the onset of the pandemic.

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“…The National Kidney Registry reported an 89% drop in LDKT in April 2020, related to concerns about donor safety and unknowns that appeared at the beginning of the pandemic with a new pathogen. It returned to more than 60% of pre-COVID-19 rates a few months later, in June 2020 [60].…”

Section: Covid-19 and Transplantation In North Americamentioning

confidence: 92%

Effects of the COVID-19 Pandemic on Solid Organ Transplantation During 2020 in Poland Compared with Countries in Western Europe, Asia, and North America: A Review

et al. 2021

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Self financingThe coronavirus disease 2019 (COVID-19) pandemic, due to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began in March 2020, affected organ donor acceptance and rates of heart, lung, kidney, and liver transplants worldwide. According to data reported to POLTRANSPLANT, the number of solid organ transplants decreased by over 35% and the number of patients enlisted de novo for organ transplantation was reduced to 70% of its pre-COVID-19 volume in Poland. Most transplant centers in Western Europe and the USA have also drastically reduced their activity when compared to the pre-pandemic era. Areas of high SARS-CoV-2 infection incidence, like Italy, Spain, and France, were most affected. Significant decreases in organ donation and number of transplant procedures and increase in waitlist deaths have been noted due to overload of the healthcare system as well as uncertainty of donor SARS-CoV-2 status. Intensive care unit bed shortages and less intensive care resources available for donor management are major factors limiting access to organ procurement. The impact of the COVID-19 outbreak on transplant activities was not so adverse in Asia, as a result of a strategy based on experience gained during a previous SARS pandemic. This review aims to compare the effects of the COVID-19 pandemic on solid organ transplantation during 2020 in Poland with countries in Western Europe, North America, and Asia.

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Trends in US Kidney Transplantation During the COVID-19 Pandemic

Cited by 10 publications

References 23 publications

Impact of COVID‐19 pandemic on the size of US transplant waiting lists

Impact of COVID‐19 pandemic on the size of US transplant waiting lists

Global Effects of SARS-CoV-2 Era on Kidney Transplantation Activities: Analysis of WHO Data

Effects of the COVID-19 Pandemic on Solid Organ Transplantation During 2020 in Poland Compared with Countries in Western Europe, Asia, and North America: A Review

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