Trends in tumors in the central nervous system in elderly in Denmark, 2008–2012

Dahlrot, Rikke Hedegaard; Poulsen, Frantz Rom; Nguyen, Nina; Kristensen, Bjarne Winther; Hansen, Steinbjørn; Holm, Niels V.

doi:10.3109/0284186x.2015.1115123

Cited by 5 publications

(6 citation statements)

References 25 publications

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“…This is in agreement with previous publications that recommended an in-depth analysis for age, gender-specific mortality rates [17] and other factors that affecting the pattern of mortality [16]. In another publication the mortality rates related to the tumors of central nervous system reported to be increased within all age groups, most significantly in patients aged 70 years or older [18]. Death reported due to multiple sclerosis in this study occurred at the age between 22 and 66 years old.…”

Section: Disscussionsupporting

confidence: 92%

“…In this study there were 19 death reports due to secondary malignant neoplasm of brain. Previous publication suggested that due to dissimilar presentation of tumor in the central nervous system, it needs dissimilar management approaches [18]. Danilova et al, in 2016 confirmed that for public health analysis data related to death should be comparable on system of producing information on cause of death across regions and/ or over time [2].…”

Section: Disscussionmentioning

confidence: 99%

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Salicylic Acid Enhances Growth and Productivity in Cabbage (Brassica oleracea var. Capitata L.) Grown Under Saline Condition

Parvin¹,

Fujita²,

Hasanuzzaman³

2017

Foc Sci

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Introduction: In a recent study of 5360 deceased records′ within a local teaching hospital in Isfahan/Iran, neurological disorders′ ranked as the main cause of mortality among others. Additionally based on previous global reports, it seems that approximately 150000 individuals die within hospital every day. Therefore the current study aims to provide an atlas for the major causes of death correlated to neurologic disorders′ in a local hospital in Isfahan/Iran. Methods: A retrospective survey of 1036 deceased individuals due to neurologic disorders′ (comprised of n = 607 males and n = 429 females), was carried out from the years 2011 to 2014. The study was conducted to Isfahan Kidney Transplantation Research Center (IKTRC). Death reported data such as age, gender, final code of death, date of admission, and duration of hospital stay were noted in Excel. The statistical analyses of d-Base were performed using SPSS (version 20) for windows. Descriptive statistics such as mean, minimum, maximum was reported for variables of interest. Results: Out of total population studied 59% were males. Age related death in the 79% was between 31 to 96 years old of life. Location of disorders that caused death were ranked as brain (n = 89%) > both brain and spinal cord (n = 5%) > spinal cord (n = 4%). Ranked reasons of death due to brain disorders resulted as: unspecified intracranial hemorrhage (n = 283; 41%) > stroke (n = 224; 32%) > traumatic intracranial injuries (n = 186; 27%) and other reasons (n = 24%). With a minimum of 1 and a maximum of 162 days, the mean hospital stay in this group was 11.9 days. In the 52% of deceased population due to spinal cord injuries, age at death was under 15 years old of life. The average hospital stay within this group of deceased before death was 15.3 days with a minimum of 1 to a maximum of 74 days. There were 7 reported deaths due to multiple sclerosis at the minimum and maximum age of 22 and 66 years old. Conclusions:The evaluation based on clinical research maps from this study could help upcoming investigation for inserting the new strategy of the multi-dimensional difference of main reasons of death due to neurological disorders in Isfahan/Iran. Finally in order to achieve for improved clinical, pharmacological or surgical performance and management, or a more profitable founding of health incomes, further study in this direction recommended.

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Section: Disscussionsupporting

confidence: 92%

Section: Disscussionmentioning

confidence: 99%

Salicylic Acid Enhances Growth and Productivity in Cabbage (Brassica oleracea var. Capitata L.) Grown Under Saline Condition

Parvin¹,

Fujita²,

Hasanuzzaman³

2017

Foc Sci

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“… 16 In terms of absolute number of people affected by neurological disorders, most of the increase in the burden was associated with ageing of the population and population growth. 9 Increasing incidence of stroke in low-income and middle-income countries, 17 increasing prevalence of multiple sclerosis, 18 , 19 increasing incidence of epilepsy in elderly people, 20 increasing prevalence of tension-type headache, 21 and increasing incidence of brain tumours in elderly people 22 have been reported elsewhere. Findings from other studies have reported that it is difficult to assess trends in prevalence and incidence of Parkinson's disease because of changes in case definitions over time.…”

Section: Discussionmentioning

confidence: 99%

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

Feigin¹,

Abajobir²,

Abate³

et al. 2017

The Lancet Neurology

1,611

853

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SummaryBackgroundComparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level.MethodsWe estimated global and country-specific prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for various neurological disorders that in the GBD classification have been previously spread across multiple disease groupings. The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson's disease, epilepsy, multiple sclerosis, motor neuron disease, migraine, tension-type headache, medication overuse headache, brain and nervous system cancers, and a residual category of other neurological disorders. We also analysed results based on the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility, to identify patterns associated with development and how countries fare against expected outcomes relative to their level of development.FindingsNeurological disorders ranked as the leading cause group of DALYs in 2015 (250·7 [95% uncertainty interval (UI) 229·1 to 274·7] million, comprising 10·2% of global DALYs) and the second-leading cause group of deaths (9·4 [9·1 to 9·7] million], comprising 16·8% of global deaths). The most prevalent neurological disorders were tension-type headache (1505·9 [UI 1337·3 to 1681·6 million cases]), migraine (958·8 [872·1 to 1055·6] million), medication overuse headache (58·5 [50·8 to 67·4 million]), and Alzheimer's disease and other dementias (46·0 [40·2 to 52·7 million]). Between 1990 and 2015, the number of deaths from neurological disorders increased by 36·7%, and the number of DALYs by 7·4%. These increases occurred despite decreases in age-standardised rates of death and DALYs of 26·1% and 29·7%, respectively; stroke and communicable neurological disorders were responsible for most of these decreases. Communicable neurological disorders were the largest cause of DALYs in countries with low SDI. Stroke rates were highest at middle levels of SDI and lowest at the highest SDI. Most of the changes in DALY rates of neurological disorders with development were driven by changes in YLLs.InterpretationNeurological disorders are an important cause of disability and death worldwide. Globally, the burden of neurological disorders has increased substantially over the past 25 years because of expanding population numbers and ageing, despite substantial decreases in mortality rates from stroke and communicable neurological disorders. The number o...

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“…There was a large rise in the absolute numbers of prevalent cases of Alzheimer's disease and other dementias ( 44 , 45 ). In addition, an increasing incidence of stroke ( 46 ), epilepsy ( 47 ), and intracranial malignancies in elderly people ( 48 ), as well as growing prevalence of multiple sclerosis ( 49 , 50 ) have been reported in different regions. The increasing burden of these neurological conditions, found to be an established risk factor for BP, may account for part of the rising incidence of BP.…”

Section: Putative Explanations For This Surgementioning

confidence: 99%

The Growing Incidence of Bullous Pemphigoid: Overview and Potential Explanations

2018

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Bullous pemphigoid (BP) is the most common type of subepidermal autoimmune bullous diseases. BP characteristically affects the elderly and is seen mainly in patients older than 70 years. While the annual incidence of BP has been estimated to be between 2.4 and 23 cases per million in the general population, it rises exponentially to 190–312 cases per million in individuals older than 80 years. In addition, a growing body of evidence reports a remarkable trend of increased incidence of BP, showing a 1.9- to 4.3-fold rise over the past two decades. This demonstrable increase warrants a higher awareness of the increased risk to develop BP. This review summarizes the current understanding of the epidemiological features of BP and sheds light on the putative explanations for its growing incidence.

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Trends in tumors in the central nervous system in elderly in Denmark, 2008–2012

Cited by 5 publications

References 25 publications

Salicylic Acid Enhances Growth and Productivity in Cabbage (Brassica oleracea var. Capitata L.) Grown Under Saline Condition

Salicylic Acid Enhances Growth and Productivity in Cabbage (Brassica oleracea var. Capitata L.) Grown Under Saline Condition

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

The Growing Incidence of Bullous Pemphigoid: Overview and Potential Explanations

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