Trends in the prevalence of isolated systolic hypertension in the middle-aged population in 1972–1992

Rl, Antikainen; Jousilahti, Pekka; Tuomilehto, J

doi:10.1038/sj.jhh.1000859

Cited by 10 publications

(6 citation statements)

References 24 publications

(36 reference statements)

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“…Other authors have reported blood pressure reductions with modest weight loss [ 39 ]. There is known to be a strong positive association between systolic blood pressure and increasing risk of stroke and cardiovascular disease, and reductions in systolic blood pressure contributes to overall CVD risk reduction [ 40 ].…”

Section: Discussionmentioning

confidence: 99%

Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk

et al. 2006

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Section: Discussionmentioning

confidence: 99%

Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk

et al. 2006

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“…14–16 The existing studies of pattern changes in rates of ISH in the US adult population focus on uncontrolled hypertension subtypes among individuals with uncontrolled blood pressure, and the prevalence and changes of untreated ISH in the general population was not the main focus. 3,17 In addition, the studies were based on the data collected two decades ago (the third National Health and Nutrition Examination Survey [NHANES III], 1988–1994).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and trends of isolated systolic hypertension among untreated adults in the United States

Rodríguez

Wang

2015

Journal of the American Society of Hypertension

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The prevalence and long–term trends of isolated systolic hypertension (ISH) among untreated adults have not been reported. Data from 24,653 participants aged ≥18 years were selected from the National Health and Nutrition Examination Survey 1999–2010. The prevalence and 95% confidence intervals (CIs) of untreated ISH were estimated by conducting the independent survey t–test. The prevalence of untreated ISH was 9.4% and decreased from 10.3% in 1999–2004 to 8.5% in 2005–2010 (P = .00248). Old persons, females, and non–Hispanic blacks had higher prevalence of untreated ISH. Compared with 1999–2004, the prevalence of untreated ISH in 2005–2010 decreased among older (33.6%; 95% CI, 30.9%–36.3% vs. 25.1%; 95% CI, 22.7%–27.5%) and female individuals (8.3%; 95% CI, 7.5–9.2% vs. 11.4%; 95% CI, 10.4–12.3%). The stratified prevalence of untreated ISH declined in 2005–2010 (vs. 1999–2004) for older non–Hispanic whites (24.6% vs. 32.8%; P < .0001) and blacks (27.7% vs. 40.8%; P = .0013), non–Hispanic white females (7.5% vs. 10.8%; P < .0001), older individuals with higher education (21.0% vs. 30.6%; P = .0024), and females with lower education (10.1% vs. 13.1%; P = .006). Untreated ISH is more prevalent in older adults and females. Significant decreases in untreated ISH prevalence over time among these groups suggest that public health measures and/or treatment patterns are trending in the right direction.

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“…1,2 The proportion of hypertensive patients with ISH has doubled over the past 20 years, 3 with Ϸ26% of the total population age Ͼ55 years affected. 4 Thus, ISH is the most common form of hypertension in the rapidly expanding older population.…”

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Aerobic Exercise Training Does Not Modify Large-Artery Compliance in Isolated Systolic Hypertension

et al. 2001

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Abstract-The present study characterized large-artery properties in patients with isolated systolic hypertension (ISH) and determined the efficacy of exercise training in modifying these properties. Twenty patients (10 male and 10 female) with stage I ISH and 20 age-and gender-matched control subjects were recruited, and large-artery properties were assessed noninvasively. Ten ISH patients (5 male and 5 female) were enrolled in a randomized crossover study comparing 8 weeks of moderate intensity cycling with 8 weeks of sedentary activity. Brachial and carotid systolic, diastolic, mean, and pulse pressures were higher in the ISH group than in the control group. Systemic arterial compliance (0.43Ϯ0.04 versus 0.29Ϯ0.02 arbitrary compliance units for the control versus ISH groups, respectively; Pϭ0.01) was lower, and carotid-to-femoral pulse-wave velocity (9.67Ϯ0.36 versus 11.43Ϯ0.51 m · s Ϫ1 for the control versus ISH groups, respectively; Pϭ0.007), input impedance (2.39Ϯ0.19 versus 3.27Ϯ0.34 mm Hg · s · cm Ϫ1 for the control versus ISH groups, respectively; Pϭ0.04), and characteristic impedance (1.67Ϯ0.17 versus 2.34Ϯ0.27 mm Hg · s · cm Ϫ1 for the control versus ISH groups, respectively; Pϭ0.05) were higher in the ISH group than in the control group. Training increased maximal oxygen consumption by 13Ϯ5% (Pϭ0.04) and maximum workload by 8Ϯ4% (Pϭ0.05); however, there was no effect on arterial mechanical properties, blood lipids, or left ventricular mass or function. These results suggest that the large-artery stiffening associated with ISH is resistant to modification through short-term aerobic training. (Hypertension. 2001;38:222-226.)

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Trends in the prevalence of isolated systolic hypertension in the middle-aged population in 1972–1992

Cited by 10 publications

References 24 publications

Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk

Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk

Prevalence and trends of isolated systolic hypertension among untreated adults in the United States

Aerobic Exercise Training Does Not Modify Large-Artery Compliance in Isolated Systolic Hypertension

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