Trends in the Incidence of First Acute Myocardial Infarction in Metropolitan and Regional Areas of the Hunter Region

Davies, Allan; Butel-Simoes, L.; Naudin, Crystal; Al-Omary, M.; Khan, Akhtar A.; Bastian, B.; Bhagwandeen, Rohan; Fletcher, Peter; Leitch, James; Boyle, Andrew

doi:10.1016/j.hlc.2018.02.022

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…Previous studies have shown a higher incidence of acute myocardial infarction in regional populations due to underutilisation of preventive therapies, representing those more likely to receive thrombolytic therapy for STEMI in our cohort. [19][20][21] Thus, comparable incidence of recurrent myocardial infarction in the two groups is reassuring for the PHT cohort.…”

Section: P-valuementioning

confidence: 82%

Pre‐hospital thrombolysis for ST‐segment elevation myocardial infarction in regional Australia: long‐term follow up

Khan

Williams

Al‐Omary

et al. 2020

Internal Medicine Journal

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Background Delivering reperfusion therapy to patients with ST‐segment elevation myocardial infarction (STEMI) in regional areas without access to tertiary cardiology care remains challenging. The systems of care in Hunter New England Health, New South Wales, Australia (area covered = 130 000 km2) to provide reperfusion to patients with STEMI involve a 12‐lead electrocardiogram in the ambulance, discussion between cardiologist and paramedic, followed by pre‐hospital thrombolysis (PHT) delivered in ambulance to appropriate patients >60 min from the cardiac catheterisation laboratories. Patients who can access the cardiac catheterisation laboratories within 60 min are treated with primary percutaneous coronary intervention (PCI). Aims We have previously reported excellent 12‐month outcomes for patients receiving PHT and the aim of the current analysis is to look at the long term outcomes. Methods We assessed long‐term all‐cause mortality and major adverse cardiovascular events of STEMI patients undergoing PHT in our health district from August 2008 to August 2013 and compared with the primary PCI group. Results One hundred and fifty (mean age: 62 ± 13 years, males: 76%, n = 114) patients were administered PHT and 334 patients (mean age: 65 ± 13 years, males: 75%, n = 251) underwent primary PCI during the study period. During a median follow up of 6.2 years (interquartile range: 4.8–7.4 years) all‐cause mortality was 16% and 19% in the PHT and primary PCI groups respectively (P = 0.4). Conclusion Our real‐world experience shows that PHT followed by early transfer to a primary PCI‐capable centre is an effective reperfusion strategy, with comparable results to primary PCI, and mortality benefits are sustained to more than 6 years.

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Section: P-valuementioning

confidence: 82%

Pre‐hospital thrombolysis for ST‐segment elevation myocardial infarction in regional Australia: long‐term follow up

Khan

Williams

Al‐Omary

et al. 2020

Internal Medicine Journal

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“…Retrospective cohort analysis involving patient data collected from the Hunter Area Cardiac and Stroke Outcomes Unit (HACSOU), which prospectively identified all admissions of MI in the Hunter‐New England Health district. The HACSOU has been previously utilised in several studies 2,18 . The use of de‐identified patient information from the database was approved by the Hunter New England Human Research Ethics Committee.…”

Section: Methodsmentioning

confidence: 99%

Impact of fast‐food outlet density on incidence of myocardial infarction in the Hunter region

Saluja

Davies

Oldmeadow

et al. 2021

Internal Medicine Journal

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Background There is an established association between fast‐food consumption and metabolic diseases. Some studies also suggest that calorie‐dense food promotes a proinflammatory response, which is itself linked with myocardial infarction (MI). Whether increased fast‐food availability is a risk factor for MI remains unknown. Aim To investigate the role of fast‐food outlet density (FFD) as a novel environmental risk factor for MI in the Hunter region, New South Wales (NSW). Methods We conducted a retrospective cohort study using a database of all MI events between 1996 and 2013, extracted from the Hunter Cardiac and Stroke Outcomes unit. FFD was calculated for each local government area (LGA) of the Hunter region, allowing for a comparative analysis. Stratification by fast‐food outlet data and LGA resulted in a total of 3070 cases. Weighted linear regression was used to investigate the role of FFD on incidence of MI in regional and rural Australia. Results FFD was positively correlated with rates of MI, remaining consistent in both single and multivariate predictor models adjusting for age, obesity, hyperlipidaemia, hypertension, smoking status, diabetes and socioeconomic status (P < 0.001). An increase of one fast‐food outlet corresponded with four additional cases of MI per 100 000 people per year (4.07, 95% confidence interval, 3.86–4.28). Conclusions FFD was positively associated with incidence of MI in both rural and metropolitan areas of NSW. This relationship remained consistent after multivariate adjustment for standard cardiovascular risk factors, highlighting the importance of an individual's food environment as a potential contributor towards their health.

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Rehabilitation Support via Postcard (RSVP): A Randomised Controlled Trial of a Postcard to Promote Uptake of Cardiac Rehabilitation

Britton¹,

Murphy²,

Jansson³

et al. 2023

Heart, Lung and Circulation

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Trends in the Incidence of First Acute Myocardial Infarction in Metropolitan and Regional Areas of the Hunter Region

Cited by 3 publications

References 9 publications

Pre‐hospital thrombolysis for ST‐segment elevation myocardial infarction in regional Australia: long‐term follow up

Pre‐hospital thrombolysis for ST‐segment elevation myocardial infarction in regional Australia: long‐term follow up

Impact of fast‐food outlet density on incidence of myocardial infarction in the Hunter region

Rehabilitation Support via Postcard (RSVP): A Randomised Controlled Trial of a Postcard to Promote Uptake of Cardiac Rehabilitation

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