Trends in the Consumption of Opioid Analgesics in Taiwan From 2002 to 2007: A Population-Based Study

Pan, Hsueh-Hsing; Ho, Shung‐Tai; Lu, Chih-Cherng; Wang, Ju-O; Lin, Tzu-Chen; Wang, Kwua-Yun

doi:10.1016/j.jpainsymman.2012.02.014

Cited by 37 publications

(34 citation statements)

References 21 publications

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“…For decades, morphine has made a large contribution to total opioid consumption in most countries 21. In our study, the DDD of morphine was lower than that of fentanyl in 2006–2014.…”

Section: Discussionmentioning

confidence: 46%

“…Opioids are extensively used for the control of cancer pain 21. However, no correlation has been found (figure 2E and F).…”

Section: Discussionmentioning

confidence: 96%

“…For decades, morphine consumption has been proposed by WHO as an indicator of cancer pain management 21. The production and consumption of morphine have significantly increased in China from 1992 to 2011 8.…”

Section: Discussionmentioning

confidence: 99%

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Consumption trend and prescription pattern of opioid analgesics in China from 2006 to 2015

Fang

Liu

et al. 2018

Eur J Hosp Pharm

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ObjectivesTo investigate the consumption trend and prescription pattern of opioids in China from 2006 to 2015, and compare the results with those of selected countries and regions, and identify the pain relief level of China.MethodsNine different opioid drugs were included in our survey, based on the whole population of China. Consumption of each type of opioid was calculated in grams in reports of the Chinese Food and Drug Administration and the International Narcotics Control Board. Then it was converted to the terms of defined daily doses and morphine equivalents. The correlation between consumption of opioids and gross domestic product, human development index and cancer incidence was analysed by Pearson’s correlation test.ResultsDefined daily doses increased by 7.89% per year since 2006, and reached 91.05 in 2015. Morphine equivalents increased by 10.57% per year since 2006, and reached 7.24 g in 2015. The average defined daily doses and morphine equivalents were 85.44 and 5.70 g respectively in 2006–2015. Annual defined daily doses of China were lower than the global average. Consumption was related to gross domestic product, but not human development index and cancer incidence. Furthermore, defined daily doses varied greatly in countries with similar gross domestic product or the human development index. Strong opioids or non-intravenous opioids always constituted the majority of opioids, and sustained an increasing tendency in consumption. The predominantly prescribed opioids were fentanyl and morphine. Consumption of oxycodone had a tendency to increase, whereas pethidine tended to decrease.ConclusionConsumption of opioids has shown an increasing tendency and in the meantime the prescription pattern has changed, indicating the progress of pain relief in China, though it remained far lower than the average global level.

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“…For decades, morphine has made a large contribution to total opioid consumption in most countries 21. In our study, the DDD of morphine was lower than that of fentanyl in 2006–2014.…”

Section: Discussionmentioning

confidence: 46%

“…Opioids are extensively used for the control of cancer pain 21. However, no correlation has been found (figure 2E and F).…”

Section: Discussionmentioning

confidence: 96%

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Consumption trend and prescription pattern of opioid analgesics in China from 2006 to 2015

Fang

Liu

et al. 2018

Eur J Hosp Pharm

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“…5 From the analysis by WHO, the morphine usage is related to the development of a country. 6,7 Although the usage of morphine in Taiwan is similar to other countries in Asia, 8 the rate is still lower than developed countries in Europe and North America. 9 From 2010 to 2014, the usage of morphine is increasing in our medical center without changing the number of hospital beds, and this indicates the improvement of pain control after implementing the pain management policy.…”

Section: Discussionmentioning

confidence: 98%

Pain management experience at a central Taiwan medical center

Tsao

Hsieh

2015

Acta Anaesthesiologica Taiwanica

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Pain management is typically more developed in western countries compared to Asia. From the accreditation standard of the Joint Commission International (JCI), there is a broad scope for pain management. In 2008, our medical center established the pain management policy, and the goal is to be a pain-free medical facility. The Framework of Pain Management Policy including: 1. the rights of patients and family members 2. Employee education 3. Assessment of pain (screening, evaluating, monitoring) 4. Patient care of pain. After implementation of pain management program, the compliance of pain assessment, the analysis of pain score before and after pain management and the analysis of Pain Management Index (PMI), all showed improvement in pain management program. The consumption of opioids usage steadily increased from 2010 to 2014. The success of our pain management program implementation could be attributed to the clear pain management policy, the firm support of higher leadership, the cooperation of IT department, and the quality control.

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“…In order to fill this knowledge gap, many developed countries calculate the total amount of opioids prescribed to cancer patients by analyzing administrative claims data or prescription database (3)(4)(5). Claims data are useful for monitoring medical utilization and prescription patterns, but it requires that its accuracy, validity and reliability are tested, so that characteristics and limitations of the dataset is well understood by those who use the data for future research (6)(7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

Accuracy of using Diagnosis Procedure Combination administrative claims data for estimating the amount of opioid consumption among cancer patients in Japan

Iwamoto

Higashi

Miura

et al. 2015

Jpn. J. Clin. Oncol.

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Trends in the Consumption of Opioid Analgesics in Taiwan From 2002 to 2007: A Population-Based Study

Cited by 37 publications

References 21 publications

Consumption trend and prescription pattern of opioid analgesics in China from 2006 to 2015

Consumption trend and prescription pattern of opioid analgesics in China from 2006 to 2015

Pain management experience at a central Taiwan medical center

Accuracy of using Diagnosis Procedure Combination administrative claims data for estimating the amount of opioid consumption among cancer patients in Japan

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