Trends in prevalence and mortality of gastroschisis and omphalocele in the United States from 2010 to 2018

Bhatt, Parth; Poku, Frank Adusei; Umscheid, Jacob; Ayensu, Marian; Parmar, Narendrasinh; Vasudeva, Rhythm; Donda, Keyur; Doshi, Harshit; Dapaah‐Siakwan, Fredrick

doi:10.1007/s12519-022-00544-2

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…This is reflected in the changes in survival rates during this time, for example, CDH mortality rates have decreased by 2.4% annually since 2001. [36][37][38][39] This introduces a time period bias when comparing the results.…”

Section: Discussionmentioning

confidence: 99%

Association between birth location and short-term outcomes for babies with gastroschisis, congenital diaphragmatic hernia and oesophageal fistula: a systematic review

Maldonado

Singhal

Chow

et al. 2023

bmjpo

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BackgroundNeonatal care is commonly regionalised, meaning specialist services are only available at certain units. Consequently, infants with surgical conditions needing specialist care who are born in non-surgical centres require postnatal transfer. Best practice models advocate for colocated maternity and surgical services as the place of birth for infants with antenatally diagnosed congenital conditions to avoid postnatal transfers. We conducted a systematic review to explore the association between location of birth and short-term outcomes of babies with gastroschisis, congenital diaphragmatic hernia (CDH) and oesophageal atresia with or without tracheo-oesophageal fistula (TOF/OA).MethodsWe searched MEDLINE, CINAHL, Web of Science and SCOPUS databases for studies from high income countries comparing outcomes for infants with gastroschisis, CDH or TOF/OA based on their place of delivery. Outcomes of interest included mortality, length of stay, age at first feed, comorbidities and duration of parenteral nutrition. We assessed study quality using the Newcastle-Ottawa Scale. We present a narrative synthesis of our findings.ResultsNineteen cohort studies compared outcomes of babies with one of gastroschisis, CDH or TOF/OA. Heterogeneity across the studies precluded meta-analysis. Eight studies carried out case-mix adjustments. Overall, we found conflicting evidence. There is limited evidence to suggest that birth in a maternity unit with a colocated surgical centre was associated with a reduction in mortality for CDH and decreased length of stay for gastroschisis.ConclusionsThere is little evidence to suggest that delivery in colocated maternity-surgical services may be associated with shortened length of stay and reduced mortality. Our findings are limited by significant heterogeneity, potential for bias and paucity of strong evidence. This supports the need for further research to investigate the impact of birth location on outcomes for babies with congenital surgical conditions and inform future design of neonatal care systems.PROSPERO registration numberCRD42022329090.

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Section: Discussionmentioning

confidence: 99%

Association between birth location and short-term outcomes for babies with gastroschisis, congenital diaphragmatic hernia and oesophageal fistula: a systematic review

Maldonado

Singhal

Chow

et al. 2023

bmjpo

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“…The prevalence of gastroschisis in the United States increased between 1995 and 2005, possibly driven by the increasing prevalence among young mothers: the percentage increase in the prevalence of gastroschisis among mothers younger than 20 years was 6.5% compared with an increase of 0.2% among mothers 35 years or older (Kirby et al, 2013). However, a more recent study showed a decline in the prevalence of gastroschisis using administrative data between 2010 and 2018 (Bhatt et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Are individual‐level risk factors for gastroschisis modified by neighborhood‐level socioeconomic factors?

Neo

Martin

Carmichael

et al. 2023

Birth Defects Research

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BackgroundTwo strong risk factors for gastroschisis are young maternal age (<20 years) and low/normal pre‐pregnancy body mass index (BMI), yet the reasons remain unknown. We explored whether neighborhood‐level socioeconomic position (nSEP) during pregnancy modified these associations.MethodsWe analyzed data from 1269 gastroschisis cases and 10,217 controls in the National Birth Defects Prevention Study (1997–2011). To characterize nSEP, we applied the neighborhood deprivation index and used generalized estimating equations to calculate odds ratios and relative excess risk due to interaction.ResultsElevated odds of gastroschisis were consistently associated with young maternal age and low/normal BMI, regardless of nSEP. High‐deprivation neighborhoods modified the association with young maternal age. Infants of young mothers in high‐deprivation areas had lower odds of gastroschisis (adjusted odds ratio [aOR]: 3.1, 95% confidence interval [CI]: 2.6, 3.8) than young mothers in low‐deprivation areas (aOR: 6.6; 95% CI: 4.6, 9.4). Mothers of low/normal BMI had approximately twice the odds of having an infant with gastroschisis compared to mothers with overweight/obese BMI, regardless of nSEP (aOR range: 1.5–2.3).ConclusionOur findings suggest nSEP modified the association between gastroschisis and maternal age, but not BMI. Further research could clarify whether the modification is due to unidentified biologic and/or non‐biologic factors.

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Ruptured giant omphalocele with congenital short small intestine: a case report

Zhang,

Wu,

Pan

et al. 2024

Front. Nutr.

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Trends in prevalence and mortality of gastroschisis and omphalocele in the United States from 2010 to 2018

Cited by 3 publications

References 14 publications

Association between birth location and short-term outcomes for babies with gastroschisis, congenital diaphragmatic hernia and oesophageal fistula: a systematic review

Association between birth location and short-term outcomes for babies with gastroschisis, congenital diaphragmatic hernia and oesophageal fistula: a systematic review

Are individual‐level risk factors for gastroschisis modified by neighborhood‐level socioeconomic factors?

Ruptured giant omphalocele with congenital short small intestine: a case report

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