Trends in nicotine consumption between 2010 and 2017 in an Australian city using the wastewater-based epidemiology approach

Mackie, Rachel; Tscharke, Benjamin J.; O’Brien, Jake; Choi, Phil M.; Gartner, Coral; Thomas, Kevin V.; Mueller, Jochen F.

doi:10.1016/j.envint.2019.01.053

Cited by 43 publications

(39 citation statements)

References 26 publications

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“…Most WBE studies have compared chemical loads over time, or between different communities, or some combination of the two. Analysis of temporal trends can monitor population chemical consumption or exposure over time, such as changes in drug use in response to government interventions such as plain cigarette packaging (11) or cannabis legalization (12). Spatial analyses can provide insights into differences in population lifestyles or behavior, such as the prevalence of illicit drug consumption in different countries (2).…”

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confidence: 99%

Social, demographic, and economic correlates of food and chemical consumption measured by wastewater-based epidemiology

Choi

Tscharke

Samanipour

et al. 2019

Proc. Natl. Acad. Sci. U.S.A.

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117

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Wastewater is a potential treasure trove of chemicals that reflects population behavior and health status. Wastewater-based epidemiology has been employed to determine population-scale consumption of chemicals, particularly illicit drugs, across different communities and over time. However, the sociodemographic or socioeconomic correlates of chemical consumption and exposure are unclear. This study explores the relationships between catchment specific sociodemographic parameters and biomarkers in wastewater generated by the respective catchments. Domestic wastewater influent samples taken during the 2016 Australian census week were analyzed for a range of diet, drug, pharmaceutical, and lifestyle biomarkers. We present both linear and rank-order (i.e., Pearson and Spearman) correlations between loads of 42 biomarkers and census-derived metrics, index of relative socioeconomic advantage and disadvantage (IRSAD), median age, and 40 socioeconomic index for area (SEIFA) descriptors. Biomarkers of caffeine, citrus, and dietary fiber consumption had strong positive correlations with IRSAD, while tramadol, atenolol, and pregabalin had strong negative correlation with IRSAD. As expected, atenolol and hydrochlorothiazide correlated positively with median age. We also found specific SEIFA descriptors such as occupation and educational attainment correlating with each biomarker. Our study demonstrates that wastewater-based epidemiology can be used to study sociodemographic influences and disparities in chemical consumption.

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confidence: 99%

Social, demographic, and economic correlates of food and chemical consumption measured by wastewater-based epidemiology

Choi

Tscharke

Samanipour

et al. 2019

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

117

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“…This has been achieved by measuring the concentration of nicotine metabolites such as cotinine and hydroxycotinine in the influent to wastewater treatment plants and using these values to estimate the nicotine consumption in the population served by the plant. [2][3][4][5] If average levels of nicotine per cigarette are also used, then these values can be converted to the number of cigarettes smoked.…”

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confidence: 99%

Anabasine‐based measurement of cigarette consumption using wastewater analysis

Bade

White

Tscharke

et al. 2020

Drug Testing and Analysis

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Community tobacco use can be monitored over time using wastewater‐based epidemiological approaches by estimating the mass loads of nicotine and its metabolites, cotinine, or hydroxycotinine, in wastewater. However, due to the use of nicotine in smoking cessation products, other sources of nicotine contribute to cotinine and hydroxycotinine loads. The use of nicotine replacement therapies could vary in space and time and mask the true rates of tobacco consumption. Therefore, this work evaluated the content of tobacco specific markers, anatabine and anabasine, in cigarettes, in urine of smokers, and in wastewater. The results indicated that the anabasine content in both licit and illicit cigarettes in Australia is less variable than anatabine and is therefore considered a better measure of tobacco consumption. A study determining the excretion of tobacco‐specific alkaloids of smoking and non‐smoking volunteers gave an average urinary mass load of anabasine of 4.38 μg/L/person and a daily mass load of 1.13 μg/day/person. Finally, this was compared with the mass loads of anabasine from wastewater‐based epidemiology data of 3 μg/day/person to estimate cigarette rates in a South Australian city: equivalent to 2.6 cigarettes/person/day. The rate of decline of cigarette use was greater when using anabasine as a measure of consumption compared with cotinine. This is the first study to estimate the rate of anabasine excretion, which can be used to estimate tobacco use independent of therapeutically prescribed nicotine.

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“…This result is similar to the approximate results in China (2.0 mg, in Dalian), America (mean 2.7 mg), Portugal, and Australia (2.5-3.5 mg). 8,9,29,30 In this study, the estimated amount of alcohol use in 11 cities of Turkey (mean 4.1 EPD) was lower than Australia (7-24 EPD), Spain S3). Therefore, the study results indicate a lower amount of daily alcohol use in Turkey compared with other countries (1.9 L) cited in the WHO's data.…”

Section: Comparison Of Wbe Results With Other Countriesmentioning

confidence: 51%

“…In the last 10 years, wastewater‐based epidemiology (WBE) has been utilized as a more objective measurement tool of nicotine and alcohol use 5–9 . Daglioglu et al conducted the first study on alcohol consumption based on WBE in the city of Adana in Turkey 10 …”

Section: Introductionmentioning

confidence: 99%

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Estimation of alcohol and nicotine consumption in 11 cities of Turkey using wastewater‐based epidemiology

Güzel

Atasoy

Gören

et al. 2021

Drug Testing and Analysis

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Alcohol and tobacco are the most frequently consumed substances in the world.Both are significantly associated with the increasing number of different diseases.Thus, monitoring nicotine and alcohol use is vital for public health planning and intervention strategies. This study aimed to calculate estimates of alcohol and nicotine use in 11 cities of Turkey using wastewater-based epidemiology. In 2019, daily composite wastewater samples from 18 wastewater treatment plants were collected for a week per season. The 24-h composite samples were collected via auto-samplers.Sample preparation for wastewater samples collected was done using liquid-liquid extraction and solid-phase extraction. Nicotine and ethyl sulfate (EtS) were analyzed using validated liquid chromatography-tandem mass spectrometry method. The estimated average nicotine consumption was 2.84 mg/p/day, and the average alcohol consumption was 3.46 ± 1.83 ml/p/day. The highest nicotine consumption was observed in Kayseri city; the highest alcohol consumption was calculated for Mersin city. In this study, the cigarette and alcohol consumption estimate obtained by wastewater-based epidemiology (WBE) was found to be higher than the Turkey Tobacco and Alcohol Market Regulatory Authority report. To our knowledge, this study is the most comprehensive one so far applied using WBE for 11 cities in Turkey and evaluates alcohol and nicotine use together.

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Trends in nicotine consumption between 2010 and 2017 in an Australian city using the wastewater-based epidemiology approach

Cited by 43 publications

References 26 publications

Social, demographic, and economic correlates of food and chemical consumption measured by wastewater-based epidemiology

Social, demographic, and economic correlates of food and chemical consumption measured by wastewater-based epidemiology

Anabasine‐based measurement of cigarette consumption using wastewater analysis

Estimation of alcohol and nicotine consumption in 11 cities of Turkey using wastewater‐based epidemiology

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