Trends in neonatal and post-neonatal tetanus admissions at a Nigerian teaching hospital

Abstract

Introduction: Tetanus accounts for high morbidity and case fatality rates in developing countries. This study therefore aimed to identify reasons for the persistence of this disease.

Renal function of post neonatal tetanus cases as seen in University of Port Harcourt Teaching Hospital

“…The case fatality rate (CFR) of tetanus in our study was 16.7%, this is comparable to the CFR of 18.2% and 18% reported by Oyedeji et al (2012) and Alhaji et al (2013) respectively. However, in a previous study carried out between 1995-2009 in UPTH by Yaguo-ide and Nte (2011) a higher CFR of 30.5% was reported, this may probably be attributed to better immunization coverage in the years after this study.…”

“…There was no significant sex difference in cases of tetanus seen in our study which contrasts with the reports from previous studies. Ojini and Danesi (2005), Oyedeji et al (2012), Oyelami et al (1996), Yaguo Ide and Nte (2011), Yaguo Ide and Nte (2012). AKI as a complication of tetanus was not seen in any of our patients however in the study carried out by Moura Filho et al ((2008) the prevalence of AKI was reported to be 11.8% while a higher prevalence of 34% was recorded by Hilton et (2006).…”

“…Most cases of post neonatal tetanus in our study was recorded among children above 5years of age which is consistent with the findings of other workers in Nigeria. Oyedeji et al (2012), Oyelami et al (1996), Alhaji et al (2013),Yaguo Ide and Nte (2011). There was no significant sex difference in cases of tetanus seen in our study which contrasts with the reports from previous studies.…”

“…Post-neonatal tetanus is a growing problem in Nigeria because it is yet to receive the attention it deserves in most developing countries, in comparison with neonatal tetanus in terms of, institution of preventive and control interventions. Oyedeji et al (2012). There is a dearth of knowledge on the renal functions of patients with post neonatal tetanus.…”

Tetanus Toxin Antibody Levels in Pre-School Nigerian Children after Three Doses of Diphtheria-Pertussis-Tetanus/Pentavalent Immunization: A Cross-Sectional Study

“…Post neonatal tetanus is an important problem in Nigeria [8] [9] [10] [11] [12]. Most studies have recognized tetanus beyond the neonatal period as a problem of enormous consequence with high case fatality rate [10] [13] [14], yet it is still seemingly disregarded and continues to afflict several children in this millennium [8] [12] [15].…”