Trends in induction of labour, 1998–2007: A population‐based study

Mealing, Nicole; Roberts, CL; Ford, Jane B.; Simpson, Judy M.; Morris, Jonathan M.

doi:10.1111/j.1479-828x.2009.01086.x

Cited by 71 publications

(49 citation statements)

References 17 publications

(19 reference statements)

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“…Increasing rates of early elective delivery before 40 weeks gestation have been reported internationally 20 22 23. Almost 90% of pregnancy hypertension and over 70% of pre-eclampsia events occur at term, but fewer pregnancies are reaching 40 weeks or beyond 7 27 40.…”

Section: Discussionmentioning

confidence: 99%

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

et al. 2011

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ObjectiveThe objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates (including gestational hypertension, pre-eclampsia and eclampsia).DesignPopulation data (from birth and/or hospital records) on all women giving birth were available from Australia (two states), Canada (Alberta), Denmark, Norway, Scotland, Sweden and the USA (Massachusetts) for a minimum of 6 years from 1997 to 2007. All countries used the 10th revision of the International Classification of Diseases, except Massachusetts which used the 9th revision. There were no major changes to the diagnostic criteria or methods of data collection in any country during the study period. Population characteristics as well as rates of pregnancy hypertension and pre-eclampsia were compared.ResultsAbsolute rates varied across the populations as follows: pregnancy hypertension (3.6% to 9.1%), pre-eclampsia (1.4% to 4.0%) and early-onset pre-eclampsia (0.3% to 0.7%). Pregnancy hypertension and/or pre-eclampsia rates declined over time in most populations. This was unexpected given that factors associated with pregnancy hypertension such as pre-pregnancy obesity and maternal age are generally increasing. However, there was also a downward shift in gestational age with fewer pregnancies reaching 40 weeks.ConclusionThe rate of pregnancy hypertension and pre-eclampsia decreased in northern Europe and Australia from 1997 to 2007, but increased in Massachusetts. The use of a different International Classification of Diseases coding version in Massachusetts may contribute to the difference in trend. Elective delivery prior to the due date is the most likely explanation for the decrease observed in Europe and Australia. Also, the use of interventions that reduce the risk of pregnancy hypertension and/or progression to pre-eclampsia (low-dose aspirin, calcium supplementation and early delivery for mild hypertension) may have contributed to the decline.

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Section: Discussionmentioning

confidence: 99%

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

et al. 2011

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“…[1][2][3][4][5] Government policy recommends that the number of women who embark on a labour and/or go into labour spontaneously needs to increase and the number of labour interventions needs to decrease such as augmentation of labour. 6 Many women require medical and/or surgical augmentation and the systematic reviews report that early amniotomy and oxytocin has a modest reduction in length of first stage of labour only and no effect on mode of birth, epidural analgesia rates or other maternal or foetal/neonatal outcomes.…”

Section: Introductionmentioning

confidence: 99%

Impact of acupressure on onset of labour and labour duration: A systematic review

2015

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“…With almost 20 % rate of induction of labour there is a rising trend in the incidence of caesarean sections and repeat caesarean deliveries. 1 Hence there is a need to address this issue. Multiple agents are used for pre-induction cervical ripening and induction of labour.…”

Section: Introductionmentioning

confidence: 99%

Oral mifepristone as adjuvant to prostaglandin E2 (PGE2) gel for preinduction cervical ripening and induction of labour in third trimester

Mane¹,

Singh

Singh³

2017

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONWhenever the intrauterine milieu is not conducive for the foetus and continuation of pregnancy may affect adversely to mother and the fetus, termination of the pregnancy is planned. If there is no contraindication for vaginal delivery then the favourability of cervix helps in predicting success of vaginal delivery. With almost 20 % rate of induction of labour there is a rising trend in the incidence of caesarean sections and repeat caesarean ABSTRACT Background: Whenever the intrauterine milieu is not conducive for the foetus and continuation of pregnancy may affect adversely to mother and the fetus, termination of the pregnancy is planned. Objective of this work was to study the safety and efficacy of oral mifepristone as adjuvant to PGE2 gel in pre-induction cervical ripening and induction of labour in third trimester. Methods: 150 patients in third trimester were recruited in this single blind randomized control trial that were planned for delivery with unfavourable cervix. They were randomly allocated into two groups i.e. study group (n = 75) who received Tab. Mifepristone 200 mg orally and control group (n = 75) who received placebo orally. At the end of 48 hours (h), change in the Bishop's Score was assessed and those with unfavourable cervix or not in labour, were administered PGE2 gel intracervically every 6h, for maximum of 3 doses for pre-induction cervical ripening of cervix. Analysis regarding safety and efficacy of the drug was done with regards to maternal and perinatal outcome. Results: Out of 150 patients, 75 received mifepristone and 75 received placebo. Mean Bishop's Score showed significant improvement after 48h in study group (R R 5.135, 95% CI 4.78 to 5.48) compared to control group (RR 3.43, 95% CI 3.21 to 3.65). Significant number of women went in spontaneous labour in study group (39 v/s 20) (p -0.035) in each dose category of PGE2 application. The opportunity to induce labour (with oxytocin) was better in study group in each dose category of intracervical PGE2 gel application. Moreover, lesser number of PGE2 gel was used in study group comparing control group. However, there were no statistical differences in both the groups as far as number of vaginal deliveries and caesearean sections are concerned. Duration of labour in both the groups was same. Neonatal and maternal morbidity was comparable in both the groups. Conclusions: Mifepristone improves Bishops score when given 48 h prior to labour induction along with increased number of spontaneous labour and reduced need for PGE2 gel applications, without increasing maternal or neonatal morbidity.

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Trends in induction of labour, 1998–2007: A population‐based study

Abstract: The pharmacological agents used for induction of labour have changed over the past decade. An important area for future research is to investigate how the dosage of oxytocin and prostaglandin affects pregnancy outcomes.

Cited by 71 publications

References 17 publications

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

Impact of acupressure on onset of labour and labour duration: A systematic review

Oral mifepristone as adjuvant to prostaglandin E2 (PGE2) gel for preinduction cervical ripening and induction of labour in third trimester

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