Trends in incidence and outcomes of gastroschisis in the United States: analysis of the national inpatient sample 2010–2014

Abstract

The incidence of neonates with gastroschisis increased between 2010 and 2014. Incidence was highest in the West. No difference in mortality and resource utilization was observed.

Gastroschisis in Finland 1993 to 2014—Increasing Prevalence, High Rates of Abortion, and Survival: A Population-Based Study

“…Complex gastroschisis with bowel damage or obstruction occurs in approximately 13 to 20% of the cases. 1,2 Up to onethird of gastroschisis patients have associated anomalies and cardiac defects are reported in up to 10% of cases. [3][4][5] Gastroschisis occurs in 2.1 to 5.3 per 10,000 live births.…”

“…[3][4][5] Gastroschisis occurs in 2.1 to 5.3 per 10,000 live births. 2,[6][7][8] For reasons unknown, the worldwide birth prevalence of gastroschisis has increased dramatically over the last decades, but these studies have lacked the total prevalence. 2,7,8 The most consistent risk factor for gastroschisis is young maternal age, but interestingly the incidence is increasing in all age groups, not only in younger women.…”

“…2,[6][7][8] For reasons unknown, the worldwide birth prevalence of gastroschisis has increased dramatically over the last decades, but these studies have lacked the total prevalence. 2,7,8 The most consistent risk factor for gastroschisis is young maternal age, but interestingly the incidence is increasing in all age groups, not only in younger women. [9][10][11][12] In general, over 90% of the gastroschisis cases are detected in prenatal ultrasound screening.…”

“…When appropriate obstetric and neonatal care are provided, the overall survival rates are above 90%. 2,7,[20][21][22] Regardless of the low mortality, gastroschisis often requires lengthy hospitalization especially in the complex cases. 2,23 Due to the associated morbidity, up to 14% of the families opt for termination of pregnancy.…”

Adherence to and outcomes of a University-Consortium gastroschisis pathway

“…While infants born with gastroschisis usually undergo abdominal closure within several days of birth, their mean hospital stay in the intensive care unit is greater than 30 days. Prolonged hospital stays are most likely because of to slow return of bowel function requiring prolonged courses of parenteral nutrition [3][4][5][6]. As a result of this protracted inpatient hospitalization, costs of treating gastroschisis reach upwards of $180,000 [3][4][5].…”