Trends in electrocardiographic abnormalities and risk of cardiovascular mortality in Lithuania, 1986–2015

Tamošiūnas, Abdonas; Petkevičienė, Janina; Radišauskas, Ričardas; Bernotienė, Gailutė; Lukšienė, Dalia; Kavaliauskas, Mindaugas; Milvidaitė, Irena; Virvičiūtė, Dalia

doi:10.1186/s12872-019-1009-3

Cited by 10 publications

(4 citation statements)

References 39 publications

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“…Данное предположение подтверждается результатами литовских исследователей, показавших, что ишемические изменения и возможный ИМ были связаны с 2,5-кратным и 4,4-кратным повышением риска смерти от ССЗ у мужчин и 1,51-кратным и 2,56-кратным повышением риска смерти от ССЗ у женщин по сравнению с лицами без или с незначительными аномалиями ЭКГ [23]. Добавление изменений на ЭКГ к традиционным ФР ССЗ несколько улучшило показатели регрессионных моделей Кокса, позволив сделать вывод о наличии связи изменений ЭКГ с повышенным риском смертности от ССЗ.…”

Section: Discussionunclassified

Myocardial infarction in the population of some Russian regions and its prognostic value

Shalnova¹,

Drapkina²,

Куценко

et al. 2022

Russ J Cardiol

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Aim. To study the prevalence of myocardial infarction (MI) in the population of Russian regions and its contribution to cardiovascular events.Material and methods. The analysis material was representative samples of the population aged 35-64 years from 11 Russian regions, examined within the multicenter study “Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation”. The response rate was about 80%. The study used a community-based systematic stratified multiply random sample. During the study, information on prior MI was obtained using a standard questionnaire. Anthropometry and measurement of blood pressure (BP) and heart rate (HR) with an automatic BP monitor were performed. Resting electrocardiography (ECG) was performed, followed by Minnesota coding. Major and minor QQS waves and STT segments were considered as ischemic ECG abnormalities. Biochemical parameters were determined using an Arkhitect 000 Clinical Chemistry Analyzer. The median prospective follow-up was 6,21 [5,25; 6,75] years. A composite endpoint (CE) was analyzed, including cardiovascular death and non-fatal MI. During the follow-up period, 363 all-cause deaths were detected, of which 134 were from cardiovascular diseases, while 196 — CEs. Statistical analysis was carried out in R 3.6.1 environment.Results. The MI prevalence among the Russian population was 2,9%; 5,2% for men and 1,5% for women, increasing with age. Men with prior MI were more likely to take statins and beta-blockers than women as follows: 39,0% vs 25,6% and 29,3% vs 27,1%, respectively. MI newly diagnosed within the follow-up period was associated with the following risk factors (RFs): smoking, increased BP, HR, triglycerides and glucose. For individuals with prior MI, a significant relationship was found only with smoking. Multiple comparison of the contribution of RFs, ECG abnormalities, and prior MI showed that the inclusion of ischemic ECG abnormalities in the analysis significantly increases the risk of cardiovascular events in individuals without prior MI compared with individuals without both MI and ECG changes. A high CE risk was noted in patients with prior MI: relative risk (RR), 4,73 (2,92-7,65); the addition of ischemic ECG abnormalities increased the RR to 5,75 (3,76-8,8).Conclusion. The RR of CEs in patients with prior MI without or with ischemic ECG changes is 4,73 and 5,75 times higher than in patients without MI and ECG abnormalities. The risk factors identified in this case cannot explain such an increase in CEs. It is obvious that people with prior MI need rehabilitation. The presence of RFs in patients with newly diagnosed MI indicates insufficient primary prevention, which suggests that strengthening preventive measures to eliminate conventional risk factors in patients with newly diagnosed MI will help reduce the risk of recurrent MI or cardiovascular mortality.

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Section: Discussionunclassified

Myocardial infarction in the population of some Russian regions and its prognostic value

Shalnova¹,

Drapkina²,

Куценко

et al. 2022

Russ J Cardiol

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“…Numerous published studies claimed high prospects of using the Minnesota Code Classi cation System of electrocardiograms (ECG) for diagnosing clinical forms of coronary artery disease (CAD) and heart failure, along with the prognosis of deaths from cardiovascular diseases [1][2][3][4][5]. The prevalence of major and minor ECG abnormalities was studied in the populations of different countries, including Belgium [6], China [7], Netherlands [8], USA [9], Pakistan [10], Brazil [11], Singapore [12], Poland [13], and Russia [14].…”

Section: Introductionmentioning

confidence: 99%

Major and minor ECG abnormalities depending on regional living conditions in Russia

Максимов¹,

Муромцева²,

Куценко³

et al. 2022

Preprint

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The goal of our study was to explore the effect of living conditions on the likelihood of major and minor ECG abnormalities on a large region scale in Russia. For the analysis, cross-sectional data of the Russian study, ESSE-RF 2013-2014, were used. They were collected on a sample of 16,400 subjects from 10 regions of the Russia. ECG abnormalities were grouped into two categories: Major and Minor (sensu the 2009 version of the Minnesota Code Classification System). Regional living conditions were considered comprehensively via five indices combining 33 characteristics of the regions. The estimates were presented as odds ratios and their 95% confidence intervals. The prevalence values of major abnormalities in the sample were 8.4% among women and 9.4% among men (p=0.021). The prevalence of minor abnormalities constituted 34.1% and 45.9%, respectively (p<0.001). In men, the likelihood of major ECG abnormalities increased with the demographic depression growth (1.08: 1.04-1.12) and with industrial development growth in the region (1.12: 1.07-1.17). In women, an increase in the likelihood of major ECG abnormalities was directly associated with industrial development (1.12: 1.07-1.16) and inversely related to the economic development in the region (0.94: 0.89-0.99). The probability of minor ECG abnormalities in men and women declined with the growth of the regional economic development: OR of 0.95: 0.93-0.98, and OR of 0.92: 0.87-0.99, respectively. The study demonstrated an effect of regional living conditions of the Russian population on the likelihood of major and minor ECG abnormalities. The most stable and logically explainable relationships were obtained for industrial and economic characteristics of living conditions.

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“…They are presented in Table 2. As evidenced by numerous published sources, ECG changes in the presented codes (primarily Major ECG abnormalities) can indicated a presence of various cardiovascular diseases, including the likelihood of developing any cardiovascular disease, myocardial infarction, coronary artery disease, heart failure, arrhythmias and death from cardiovascular disease [1][2][3][4][5] .…”

mentioning

confidence: 99%

Major and minor ECG abnormalities depending on regional living conditions in Russia

Максимов

Муромцева

Куценко

et al. 2023

Sci Rep

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The goal of our study was to explore the effect of living conditions on the odd of major and minor ECG abnormalities on a large region scale in Russia. For the analysis, cross-sectional data of the Russian study, ESSE-RF 2013–2014, were used. They were collected on a sample of 16,400 subjects from 10 regions of the Russia. ECG abnormalities were grouped into two categories: Major and Minor (sensu the 2009 version of the Minnesota Code Classification System). Regional living conditions were considered comprehensively via five indices combining 33 characteristics of the regions. The estimates were presented as odds ratios and their 95% confidence intervals. The prevalence values of major abnormalities in the sample were 8.4% among women and 9.4% among men (p = 0.021). The prevalence of minor abnormalities constituted 34.1% and 45.9%, respectively (p < 0.001). In men, the odd of major ECG abnormalities increased with the demographic depression growth (1.08: 1.04–1.12) and with industrial development growth in the region (1.12: 1.07–1.17). In women, an increase in the odd of major ECG abnormalities was directly associated with industrial development (1.12: 1.07–1.16) and inversely related to the economic development in the region (0.94: 0.89–0.99). The odd of minor ECG abnormalities in men and women declined with the growth of the regional economic development: OR of 0.95: 0.93–0.98, and OR of 0.92: 0.87–0.99, respectively. The study demonstrated an effect of regional living conditions of the Russian population on the odd of major and minor ECG abnormalities. The most stable and logically explainable relationships were obtained for industrial and economic characteristics of living conditions.

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Trends in electrocardiographic abnormalities and risk of cardiovascular mortality in Lithuania, 1986–2015

Cited by 10 publications

References 39 publications

Myocardial infarction in the population of some Russian regions and its prognostic value

Myocardial infarction in the population of some Russian regions and its prognostic value

Major and minor ECG abnormalities depending on regional living conditions in Russia

Major and minor ECG abnormalities depending on regional living conditions in Russia

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