Trends in drug use among young adult females: a 22-year retrospective analysis

Clifford, Eric; Kilgore, Phillip; Cvek, Urška; Trutschl, Marjan; Baker, Stephen; Conrad, Steven A.; Arnold, Thomas C.; Korneeva, Nadejda L.

doi:10.1080/24734306.2022.2110201

Cited by 1 publication

(6 citation statements)

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“…This result suggests that while in the hospital CC and AA these mothers have equal access to opiate treatment, outside of the hospital CC population probably has an easier access to opiates. This agrees with our previous study in which we observed a higher percentage of opiate-positive UDS in CC females compared to that in AA population [ 17 ]. Opioid exposure early in life may lead to opioid dependence.…”

Section: Discussionsupporting

confidence: 93%

“…In our recent study of UDS results for 18–35 y.o. females, we observed a similar trend [ 17 ]. These results suggest that mother’s drugs use habits influence what drugs their children are involuntarily exposed to during early life.…”

Section: Discussionsupporting

confidence: 83%

“…During both periods, the majority of tests were performed for AA (~75%) and CC children (~20%), similar to the population of neonate mothers tested during 2012–2019: 72% and ~25% for AA and CC mothers, respectively. Interestingly, these demographic profiles differed from the population of young females of childbirth age tested in the hospital during 2012–2019: 63% AA and 35% CC [ 17 ], which is close to the population distribution of Shreveport: 57% AA and 31% CC [ 19 ]. These data suggest that females who gave birth at the LSUHSC-S preferred to bring their children to LSUHSC-S in case of emergency.…”

Section: Discussionmentioning

confidence: 84%

“…In our previous study, we observed a similar trend among young females of childbearing ages. CC females had up to 5-fold higher percentage of benzodiazepine positive UDS records compared to AA females during 1998–2019 [ 17 ]. These results indicate that both the in-hospital and outside of hospital CC population has higher rate of benzodiazepine use compared to AA population.…”

Section: Discussionmentioning

confidence: 99%

“…In our previous study, we identified the trends of urine drug screen (UDS) results for 18–35 years old women that visited Louisiana State University Health Sciences Center in Shreveport (LSUHSC-S) during the 1998–2019 period [ 17 ]. We found that African American (AA) females had a higher percentage of positive UDS results for illicit drugs (cannabinoids and cocaine), while Caucasian (CC) females had a higher percentage of positive UDS results for prescription drugs (opiates, benzodiazepines, and amphetamines).…”

Section: Introductionmentioning

confidence: 99%

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Trends in Drug Tests among Children: A 22-Year Retrospective Analysis

et al. 2023

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There are several pathophysiological outcomes associated with substance abuse including metabolic disbalance, neurodegeneration, and disordered redox. Drug use in pregnant women is a topic of great concern due to developmental harm which may occur during gestation and the associated complications in the neonate after delivery. We sought to determine what the trajectory of drug use is like in children aged 0–4 years and mothers of neonates. Urine drug screen (UDS) results were obtained of our target demographic during 1998–2011 and 2012–2019 from LSU Health Sciences Center in Shreveport (LSUHSC-S). Statistical analysis was performed using R software. We observed an increase in cannabinoid-positive UDS results in both Caucasian (CC) and African American (AA) groups between 1998–2011 and 2012–2019 periods. Cocaine-positive UDS results decreased in both cohorts. CC children had higher UDS positive results for opiates, benzodiazepines, and amphetamines, while AA children had a higher percentage for illicit drugs such as cannabinoids and cocaine. Neonate’s mothers had similar UDS trends to that in children during 2012–2019. Overall, while percentage of positive UDS results for both AA and CC 0–4 year old children started to decline for opiate, benzodiazepine, and cocaine during 2012–2019, cannabinoid- and amphetamine (CC)-positive UDS steadily increased. These results suggest a shift in the type of drug use by mothers from opiates, benzodiazepines, and cocaine to cannabinoids and/or amphetamines. We also observed that 18-year-old females who tested positive for opiates, benzodiazepine, or cocaine had higher than average chances of testing positive for cannabinoids later in life.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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