Trends in Drug Prescription Rates for Dementia: An Observational Population-Based Study in France, 2006–2014

Abstract

Drugs prescribed for dementia are on a declining trend with important cost savings, and this was concomitant with guidance updates that left physicians to rely on their clinical expertise while managing dementia.

Determinants of antidementia drug prescription in patients older than 65: A latent class analysis

“…But this influence is not unambiguous. On the one hand, patients treated in 2012 have probably a higher probability of being treated in 2013: recent work shows that over this period, the decrease in antidementia drugs prescription is essentially related to the decrease in the initiation of these treatments rather than to a decrease in their renewal . On the other hand, patients who have already been treated between 2006 and 2013 and who have stopped their treatment before 2013 due to lack of effectiveness or existence of adverse effects are probably less likely to receive treatment in 2013.…”

“…Patients with dementia raise therapeutic challenges as they constitute a heterogeneous population with various combinations of age, types of dementia, severity, and comorbidities . Antidementia drugs, that is, cholinesterase inhibitors (ChEIs) and memantine, have been widely prescribed in the past fifteen years despite the ongoing debate regarding their effectiveness . In addition, these treatments have been found to be associated with adverse effects that may require hospitalization (e.g., gastrointestinal or cardiovascular symptoms) for the most fragile patients …”

“…Even if the effectiveness of cognitive and physical interventions is controversial, their use is encouraged because of their limited adverse effects . Since the updating of the guidelines, the recent literature has highlighted a significant decline in the prescription of antidementia drugs in European countries with important cost savings . However, rates of prescriptions remain significant .…”

“…Since the updating of the guidelines, the recent literature has highlighted a significant decline in the prescription of antidementia drugs in European countries with important cost savings . However, rates of prescriptions remain significant . Persistent physicians' prescription habits can be explained by the difficulty in stopping a long‐standing treatment even if the treatment does not prove its effectiveness .…”

O Uso Prolongado De Benzodiazepínicos Por Idosos E O Risco Para Demência

“…O envelhecimento ativo pode ser definido como resiliência, pode acessar as reservas necessárias para se adaptar, suportar e aprender com os desafios que vão surgindo ao longo da vida e que a saúde, segurança financeira, conhecimentos e habilidades representam as reservas para conseguir o crescimento pessoal, que levam ao bem-estar e à qualidade de vida(WHO, 2005). Os efeitos dessa doença progressiva são desgastantes nas famílias, que passam a apresentar maior risco de declínio da própria saúde física e emocional(ISMAIL et al, 2011; OTA et al, 2015;CUSTODIO et al, 2017;FRANÇOIS et al, 2017). dos países ricos, que tiveram o privilégio de enriquecer antes de envelhecer, tem programas e ambientes sociais, que de alguma forma vão suprir as necessidades dessa população, garantindo a sustentabilidade de todas as gerações(PINCUS et al, 2017).…”