Trends in cardiovascular mortality and hospitalisations, and potential contribution of inhospital case-fatality rates to changes in national mortality in the Czech Republic 1994–2009

Davídkovová, Hana; Kyselý, Jan; Kříž, B; Vojtíšek, Petr; Bobák, Martin

doi:10.1136/heartjnl-2012-303123

Cited by 15 publications

(13 citation statements)

References 43 publications

(47 reference statements)

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“…22 Thus, the mortality trends we presented here are consistent with those reported for other European countries, although our study shows a more pronounced change of slope than other studies. Our study benefits from examining the longest follow-up period reported so far.…”

Section: Original Articlesupporting

confidence: 81%

Trends in heart failure mortality in Poland between 1980 and 2010

Rywik¹,

Koziarek²,

Piotrowski³

et al. 2013

Polish Archives of Internal Medicine

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IntroductIon Data regarding standardized trends in mortality from heart failure (HF) in the general population are limited.objEctIvEs The aim of the study was to evaluate trends in HF mortality in Poland in the years 1980-2010. PAtIEnts And mEthods An analysis of a database of mortality records from 1980-2010 based on National Statistics was performed. Mortality trends for HF by age and sex were analyzed by polynomial or linear regression.rEsuLts Total crude numbers of HF deaths in 1980 were 21,519 and 23,008 for women and men, respectively, whereas, in 2010, there were 23,304 and 19,558. There was a significant change in mortality trends for HF, from a decline during the first phase of the study to an increase during the most recent years, 2005-2010 (P <0.005 for changes of trends for both sexes). The lowest value reached in 2005 constituted 47% and 41% of the baseline for women and men, respectively. These ratios increased to 59% and 52% in 2010. Stratification by age and sex brought similar results, with the exception of the youngest groups, which showed initial increases in the rates for the years 1980-1985. concLusIons There was a significant decline in the rates of HF mortality in the Polish population for both men and women, showing a maximal reduction of about 50% around 2005. However, between 2005 and 2010, a significant increase in the rates of HF mortality was observed (crude difference equaled 12% for women and 11% for men). It is unknown whether this is a temporary or permanent trend, and the issue requires further investigation. KEy wordsheart failure, mortality, prognosis orIGInAL ArtIcLE Trends in heart failure mortality in Poland between 1980 and 2010 665 rates of HF deaths declined for both women and men. The lowest values registered were 141.8 for women and 214.2 for men in 2005, which constituted 47% and 41% of the 1980 death rates, respectively. Subsequently, death rates increased between 2005 and 2010 (women -176.5 and men -268.7), reaching 59% and 52% of the baseline values (FIGurE 1). A polynomial analysis (FIGurE 2) showed that the trends changed significantly twice during the follow-up in men and women, from a declining trend through 2005, followed by a recently emerging increase (P <0.005).Age groups Stratifying by age groups revealed a positive association between age and crude HF mortality rates for both sexes with the highest values in the oldest subjects throughout the study period (FIGurEs 3 and 4).Trend analysis in the youngest groups (45-64 years) showed that for both sexes death rates for HF increased during the initial phase of the study, reaching their peak around [1985][1986][1987][1988][1989][1990]. After that, the rates declined reaching their nadir around 2005. The rates of HF deaths for this younger subgroup declined from 51.7 to 19.9 for women (38% of the initial values) and from 135.0 to 65.1 for men (48%) between 1980 and 2005. However, during the years 2005-2010, an increase was observed. As a result, standardized HF rates reached 27.8 for women and 95.6 f...

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Section: Original Articlesupporting

confidence: 81%

Trends in heart failure mortality in Poland between 1980 and 2010

Rywik¹,

Koziarek²,

Piotrowski³

et al. 2013

Polish Archives of Internal Medicine

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“…Hospital admissions and deaths due to cardiovascular disease (CVD) complications and stroke reach a marked peak during winter months and drop in summer months, even in moderate climates (Davidkovova et al, 2013;Spencer et al, 1998). Several contributing factors can form a backdrop to these results, i.e.…”

Section: Introductionmentioning

confidence: 97%

Could human cold adaptation decrease the risk of cardiovascular disease?

Lesná

Rychlikova

Vávřová

et al. 2015

Journal of Thermal Biology

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“…This resulted in improved levels of hypertension control (men, 3% to 24%; women, 5% to 25%) [61]. These improvements in hypertension control could explain the observed reductions in CV death in the Czech Republic over time (from 561 per 100 000 [1994] to 357 per 100 000 [2009]) [62].…”

Section: Discussionmentioning

confidence: 99%

Simulating the Impact of Improved Cardiovascular Risk Interventions on Clinical and Economic Outcomes in Russia

Shum¹,

Alperin²,

Шальнова

et al. 2014

PLoS ONE

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ObjectivesRussia faces a high burden of cardiovascular disease. Prevalence of all cardiovascular risk factors, especially hypertension, is high. Elevated blood pressure is generally poorly controlled and medication usage is suboptimal. With a disease-model simulation, we forecast how various treatment programs aimed at increasing blood pressure control would affect cardiovascular outcomes. In addition, we investigated what additional benefit adding lipid control and smoking cessation to blood pressure control would generate in terms of reduced cardiovascular events. Finally, we estimated the direct health care costs saved by treating fewer cardiovascular events.MethodsThe Archimedes Model, a detailed computer model of human physiology, disease progression, and health care delivery was adapted to the Russian setting. Intervention scenarios of achieving systolic blood pressure control rates (defined as systolic blood pressure <140 mmHg) of 40% and 60% were simulated by modifying adherence rates of an antihypertensive medication combination and compared with current care (23.9% blood pressure control rate). Outcomes of major adverse cardiovascular events; cerebrovascular event (stroke), myocardial infarction, and cardiovascular death over a 10-year time horizon were reported. Direct health care costs of strokes and myocardial infarctions were derived from official Russian statistics and tariff lists.ResultsTo achieve systolic blood pressure control rates of 40% and 60%, adherence rates to the antihypertensive treatment program were 29.4% and 65.9%. Cardiovascular death relative risk reductions were 13.2%, and 29.6%, respectively. For the current estimated 43,855,000-person Russian hypertensive population, each control-rate scenario resulted in an absolute reduction of 1.0 million and 2.4 million cardiovascular deaths, and a reduction of 1.2 million and 2.7 million stroke/myocardial infarction diagnoses, respectively. Averted direct costs from current care levels ($7.6 billion [in United States dollars]) were $1.1 billion and $2.6 billion, respectively.

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Trends in cardiovascular mortality and hospitalisations, and potential contribution of inhospital case-fatality rates to changes in national mortality in the Czech Republic 1994–2009

Abstract: During the study period, the overall CVD hospitalisation rates remained high but inhospital CFR declined considerably. The improved case-fatality seems to have made a substantial contribution to the decline in the national CVD mortality, particularly for AMI and stroke.

Cited by 15 publications

References 43 publications

Trends in heart failure mortality in Poland between 1980 and 2010

Trends in heart failure mortality in Poland between 1980 and 2010

Could human cold adaptation decrease the risk of cardiovascular disease?

Simulating the Impact of Improved Cardiovascular Risk Interventions on Clinical and Economic Outcomes in Russia

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