Trends in cancer incidence in Connecticut, 1935–1991

Abstract

Background. This study used data from the population‐based Connecticut Tumor Registry, a unique resource for examining secular trends in cancer incidence rates since 1935. Methods. Trends in average annual age‐standardized incidence rates (ASRs) for invasive cancers in Connecticut residents were examined from 1935‐1939 to 1990‐1991. Results. Trends in ASRs were complex, with some sites showing large increases but others only small changes since 1935‐1939. Declines were evident for stomach and cervical since 1935‐1939 and for colorectal cancer after 1980‐1984. Since 1965‐1969, when 2% or less of cancers were ascertained only by death certificates, exclusion of cancers of the breast and prostate (strongly affected by increased screening), smoking‐related cancers, and cancers of other sites with identified causes (melanoma and human immunodeficiency virus‐related cancers), resulted in little or no increase in the ASRs for all other sites combined. For young (20–44‐year‐old) adults, unexplained increases since 1965‐1969 were limited to testicular cancer and Hodgkin's disease. Conclusions. Reducing cancer incidence rates will require expanded primary prevention efforts (mainly involving behavioral changes) and more etiologic research on common cancers whose causes are poorly understood (e. g., breast and prostate cancer) and rarer cancers showing unexplained recent increases (i. e., testicular cancer and Hodgkin's disease).

Cancer mortality in four northern wheat-producing states.

“…Several cancers, especially prostate cancer, have been on the rise for several decades in the general population, mostly in the United States and Western Europe (43,44,51,52). The herbicides 2,4-D and MCPA, used since the Second World War, are widely applied for domestic use in many countries.…”

Trends in cancer incidence and mortality in Vaud, Switzerland, 1974–1993

“…When trends in incidence differ from those in mortality, in fact, it is possible to infer the probable role of improved diagnosis in increasing incidence rates, and the one of therapeutic advancement in reducing mortality [1][2][3][4][5][6][7][8][9][10][11][12].…”

Modeling Dose Deposition and DNA Damage Due to Low-Energy β–Emitters

“…It should be noted that improvements in treatment during the latter period led to increases in cure rates for this disease. As shown in Figure 4B.2, data from longrunning cancer registries in Connecticut ( (Heston et al, 1986;Connecticut Tumor Registry, 2001;Polednak, 2001Polednak, , 2003 and Saskatchewan, Canada (Wang and Haines, 1995), do not indicate the same type of decrease in leukaemia incidence rates in the 1970s as do the mortality data reported by Archer. However, the cancer registry data are sparser since they relate to smaller populations.…”