2002
DOI: 10.2188/jea.12.217
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Trends in Asthma Morbidity and Mortality in Japan between 1984 and 1996.

Abstract: Purpose: To determine whether the increased prevalence of asthma in Japan has influenced its mortality. Materials and Methods: A descriptive study was conducted by the data obtained from Patient Survey and Vital Statistics of Japan between 1984 and 1996. Asthma fatalities were expressed as the number of deaths from asthma per 100,000 asthmatic patients receiving medical treatment on the day when the survey was conducted. Results: Mortality, prevalence and asthma fatalities showed different changing patterns am… Show more

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Cited by 12 publications
(12 citation statements)
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“…The incidence of asthma is continually increasing, and together with its secondary effects, which include increased susceptibility to viral infection (2,9,16,22,26,36,61), constitutes an enormous public health problem. Inflammatory cells and cytokines, bronchoconstriction, and airway wall remodeling all act synergistically to exacerbate the disease, and the enhanced epithelial susceptibility to viral pathogens and particulate matters also aggravates symptoms.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The incidence of asthma is continually increasing, and together with its secondary effects, which include increased susceptibility to viral infection (2,9,16,22,26,36,61), constitutes an enormous public health problem. Inflammatory cells and cytokines, bronchoconstriction, and airway wall remodeling all act synergistically to exacerbate the disease, and the enhanced epithelial susceptibility to viral pathogens and particulate matters also aggravates symptoms.…”
Section: Discussionmentioning
confidence: 99%
“…This finding has significance for asthma pathophysiology as well as for designing delivery strategies of viral gene therapies to the airways. mechanical stress; three-dimensional model; asthma; bronchoconstriction; ciliogenesis; human ASTHMA AND AIRWAY SUSCEPTIBILITY to viral infections have long been correlated clinically (2,9,16,26,36,61,62). Asthma is associated with recruitment of inflammatory cells, remodeling and thickening of the reticular basement membrane, subepithelial fibrosis, and airway smooth muscle hyperresponsiveness and hyperreactivity (reviewed in Refs.…”
mentioning
confidence: 99%
“…In many countries, the majority of asthma-related deaths involves elderly patients (65 years) [4,5]. Based on aging of the population of Japan, the proportion of elderly asthmatics is increasing according to The Ministry of Health, Labour and Welfare of Japan (reported in 2010 in Japanese only).…”
Section: Introductionmentioning
confidence: 99%
“…Tanihara described the increasing morbidity (number of patients under treatment per population) of asthma in Japan since 1984 (4) and reported the economic impact of increasing asthma prevalence on Japan's national medical care expenditure (5). Overall, asthma is considered as one of the most important childhood diseases in developed countries (6).…”
Section: Introductionmentioning
confidence: 99%