Trends in antibiotic resistance among bacteria isolated from blood cultures using a large private laboratory network data in India: 2008-2014

Gandra, Sumanth; Mojica, Nestor; Ashok, Ashvin; Das, B. K.; Laxminarayan, Ramanan

doi:10.1186/2047-2994-4-s1-o42

Cited by 4 publications

(2 citation statements)

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“…In 2015, Gandra et al observed that 26% of isolates were coagulase negative staphylococcus between 2008 to 2014 and he quoted that, Methicillin Resistant Staphylococcus Aureus (MRSA) was 55% during 2014, while we found that during early 2017 to late 2018, there was 25.12% Staphylococcus aureus were resistance to methicillin. 6 We also observed that, In 37.67% Staphylococcus aureus isolates were resistant to vancomycin while 46.83% were sensitive (p<0.0001), Menezes et al also indicated the emergence of Vancomycin Intermediate Resistant Staphylococcus Aureus (VISA) species in southern India. 14 More than 40% stool samples were tested positive for Escherichia coli (E. coli) and it was second comments isolated organism both in male and female patients.…”

Section: Discussionsupporting

confidence: 55%

“…Furthermore, following the similar principle in many diseases such as spontaneous bacterial peritonitis, lung infection in ICU patients, middle ear infection, sinusitis, throat infection, penetrating gut injury and community acquired pneumonia short course regimens were followed. 6 To combat AMR, world Health Organization (WHO) initiate a program for the development of a new class of antibiotics to replace the older generation of without losing their effect and a new strategy to protect newer drugs and reduce the intensity of antimicrobial resistance globally in future. [7][8][9] The surveillance of AMR is essential to track changes in microbial populations, estimate the magnitude of the problem and to design and evaluate interventions.…”

Section: Introductionmentioning

confidence: 99%

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Antibiotics sensitivity and resistant pattern in tribal region of Chhattisgarh, India: a retrospective observational study

Bharti¹,

Sharma²,

Sharma³

et al. 2019

Int J Basic Clin Pharmacol

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Background: Antimicrobial resistance (AMR) is the biggest health care problem globally, it is responsible for the high rate of mortality worldwide which was commonly observed in developing countries. We tried to find the incidence of antimicrobial resistance in the tribal region of Chhattisgarh, India.Methods: It was an institutional based retrospective observational study. Out of 3389 samples from inpatient and outpatient department, a total number of 1676 cultured proven micro-organism were isolated from Jan 2017 to Dec 2018. SPSS v23 was used for descriptive analysis.Results: More than 75% of the samples collected from the inpatient department in which surgical IPD were significantly higher. The commonest isolated were Staphylococcus aureus followed by Escherichia coli, then Klebsiella species. Amoxycillin-clavulanic acid was resistant to the majority of microorganism followed by 3rd generation cephalosporins then Co-trimoxazole.Conclusions: Antimicrobial resistance was higher even in the tribal region. The incidence of AMR is increasing at an alarming rate. Microorganism targeted antimicrobial therapy with the use of narrow-spectrum antibiotics and avoidance of broad-spectrum antibiotics will possibly overcome the antimicrobial resistance. There is also a need to strengthen laboratory or microbiology department to produce an accurate report to combat antimicrobial resistance.

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Section: Discussionsupporting

confidence: 55%

Section: Introductionmentioning

confidence: 99%