Trends in 28‐day and 1‐year mortality rates in patients hospitalized for a first acute myocardial infarction in Norway during 2001–2009: a “Cardiovascular disease in Norway” (CVDNOR) project

Abstract

Objective. The aim of this study was to investigate the trends in 28-day and 1-year mortality rates in patients hospitalized for a first acute myocardial infarction (AMI) in Norway during the period 2001-2009. Potential age group and gender differences in these trends were also examined.Design, subjects and setting. In this retrospective nationwide cohort study, patients hospitalized for a first AMI between 2001 and 2009 were identified in the Cardiovascular Disease in Norway 1994-2009 (CVDNOR) project and followed for 1 year.Main outcome measures. Trends in 28-day and 1-year mortality [both all-cause and cardiovascular disease (CVD) mortality] were investigated.Results. A total of 115 608 patients (60.6% men) were hospitalized for a first AMI during the study period. Mortality at 28 days was reduced annually by 3.8% overall and by 6.7%, 4.1% and 2.6% in patients aged 25-64, 65-84 and ≥85 years, respectively (all P trend < 0.001). In addition, 1-year all-cause mortality was reduced annually by 2.0% overall (P trend < 0.001) and by 3.7% (P trend = 0.02), 2.5% (P trend < 0.001) and 1.1% (P trend < 0.001) in patients aged 25-64, 65-84 and ≥85 years, respectively. Furthermore, 1-year CVD mortality was reduced overall by 6.2% annually; a reduction was observed in all age groups. Finally, 1-year non-CVD mortality increased annually overall by 3.9% due to an increase in patients aged ≥65 years.Conclusion. Mortaity at 28 days after the first AMI declinedin Norway between 2001 and 2009 in both men and women and in all age groups. All-cause mortality at 1 year also declined both in men and women due to decreases in CVD mortality rates, whilst non-CVD mortality rates increased amongst patients ≥65 years of age.

Improving 30-day case fatality after incident myocardial infarction in people with diabetes between 1998 and 2010

“…Case fatality following MI has decreased in community-based and population-based settings since late 1980s,4–6 19 with indications that these downward trends are also apparent in patients with diabetes 7–9 20. In contrast, an earlier Australian study of a MONICA population found no reduction in 28-day case fatality after incident MI in patients with diabetes from 1985 to 1994 21.…”

Time Trends and Educational Inequalities in Out‐of‐Hospital Coronary Deaths in Norway 1995–2009: A Cardiovascular Disease in Norway (CVDNOR) Project

“…Although OHCDs in younger individuals comprise only 10% of all OHCDs, they account for a substantial number of years of potential life lost and often affect active members of the workforce and parents caring for children. Recent literature has shown that in‐hospital mortality among younger individuals is very low and decreasing . Thus, if younger individuals with signs and symptoms compatible with acute coronary syndrome are quickly admitted to hospitals, coronary mortality may be substantially reduced in this group.…”

“…Recent literature has shown that in-hospital mortality among younger individuals is very low and decreasing. 30 Thus, if younger individuals with signs and symptoms compatible with acute coronary syndrome are quickly admitted to hospitals, coronary mortality may be substantially reduced in this group. Efforts are needed to increase public awareness of CHD as a lifethreatening condition requiring immediate medical assistance.…”

A study of risk factors and clinical profile of patients with acute myocardial infarction

“…Second attacks are relatively less in number but if it happens carries a very poor prognosis mostly ending in death and thus increasing the mortality due to AMI. 1 New cases of AMI tell us about the prevalence of risk factors in the community which lead to increased incidence of AMI. On the other hand, the occurrence of repeated attacks of AMI tells us about the quality of care received by the patient during the attack of AMI and its subsequent treatment.…”