Trends, characteristics, and incidence of anaphylaxis in 2001-2010: A population-based study

Lee, Sangil; Hess, Erik P.; Lohse, Christine M.; Gilani, Waqas I; Chamberlain, Alanna M.; Campbell, Ronna L.

doi:10.1016/j.jaci.2016.04.029

Cited by 121 publications

(97 citation statements)

References 38 publications

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“…We identified patients with anaphylaxis from the Rochester Epidemiology Project (REP), a medical record linkage system connecting the records of all health care providers in Olmsted County, Minnesota. 10–14 Every patient’s diagnosis was coded with either the codes of the Hospital Adaptation of the International Classification of Diseases (HICDA), Second Edition, or the codes of the International Classification of Diseases (ICD-9), Ninth Edition. This study was approved by the Mayo Clinic and Olmsted Medical Center Institutional Review Boards.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Rate of recurrent anaphylaxis and associated risk factors among Olmsted County, Minnesota, residents

Lee

Bashore

Lohse

et al. 2016

Annals of Allergy, Asthma & Immunology

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Section: Methodsmentioning

confidence: 99%

“…This methodology is similar to a prior study of anaphylaxis in Olmstead County which utilized REP resources. 14, 15 …”

Section: Methodsmentioning

confidence: 99%

Rate of recurrent anaphylaxis and associated risk factors among Olmsted County, Minnesota, residents

Lee

Bashore

Lohse

et al. 2016

Annals of Allergy, Asthma & Immunology

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“…In a nearly global manner and for reasons not fully understood, the incidence of anaphylaxis has increased [3][4][5], as has its severity [6][7][8]. This explains the growing interest in epidemiological surveys to map the problem in several populations.…”

Section: Discussionmentioning

confidence: 99%

“…Three prior studies using data from the Rochester Epidemiology Project have studied the incidence of anaphylaxis among residents of Olmsted County, Minnesota, USA, over different time periods, which together span from 1983 to 2010 [3][4][5]. Their findings suggest that the incidence of anaphylaxis is increasing in that population, in both children and adults.…”

Section: Introductionmentioning

confidence: 99%

Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies

Gagete¹,

Santos²,

Pontes³

et al. 2017

World Allergy Organization Journal

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Background: The incidence of anaphylaxis is increasing in several parts of the world; thus, determining the prevalence of the disease in a given region is important to understand the factors involved and to promote measures to avoid this type of allergic reaction. Aiming this objective, we validated an instrument for a populationbasedstudy that assesses the prevalence of anaphylaxis in the Brazilian population. Methods: A questionnaire was generated in two variants -one for subjects seven years old or above (Group A) and another for children who were up to six years, 11 months and 29 days (Group B). The instrument was administered to patients with and without anaphylaxis. By allocating points, a score was calculated to differentiate subjects with and without the disease. After validation, the questionnaire was applied in the city of Botucatu (São Paulo state, Brazil), by randomly selecting houses and inviting residents to answer the questionnaire. Results: The questionnaire was reliable for identifying subjects with and without anaphylaxis in both groups, with a specificity and sensitivity above 90%. The prevalence of anaphylaxis in the pilot survey was 6.2% in Group A, however the evaluation was compromised in Group B by the low number of children below seven years of age due to random sampling of residences. Discussion: The prevalence of anaphylaxis in our pilot test (6.2%) was similar to major epidemiological surveys from several parts of the world, showing that anaphylaxis is not a rare disease. The instrument of the present work was suitable for this epidemiological survey and might be a good option for studying anaphylaxis in other populations. Conclusion: This instrument might be of particular value in places where researchers cannot access medical records to conduct similar epidemiological studies.

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“…These findings likely underestimate the frequency of anaphylaxis in the ED due to underdiagnosis. More recent data indicate that ED visits for anaphylaxis are increasing 21. However, this may be due, at least in part, to increased recognition rather than a true increase in incidence; nevertheless, anaphylaxis continues to be a relatively infrequent emergency in the ED.…”

Section: Discussionmentioning

confidence: 99%

Autoinjectors Preferred for Intramuscular Epinephrine in Anaphylaxis and Allergic Reactions

Campbell

Bellolio

Motosue

et al. 2016

WestJEM

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IntroductionEpinephrine is the treatment of choice for anaphylaxis. We surveyed emergency department (ED) healthcare providers regarding two methods of intramuscular (IM) epinephrine administration (autoinjector and manual injection) for the management of anaphylaxis and allergic reactions and identified provider perceptions and preferred method of medication delivery.MethodsThis observational study adhered to survey reporting guidelines. It was performed through a Web-based survey completed by healthcare providers at an academic ED. The primary outcomes were assessment of provider perceptions and identification of the preferred IM epinephrine administration method by ED healthcare providers.ResultsOf 217 ED healthcare providers invited to participate, 172 (79%) completed the survey. Overall, 82% of respondents preferred the autoinjector method of epinephrine administration. Providers rated the autoinjector method more favorably for time required for training, ease of use, convenience, satisfaction with weight-based dosing, risk of dosing errors, and speed of administration (p<0.001 for all comparisons). However, manual injection use was rated more favorably for risk of provider self-injury and patient cost (p<0.001 for both comparisons). Three participants (2%) reported a finger stick injury from an epinephrine autoinjector.ConclusionED healthcare providers preferred the autoinjector method of IM epinephrine administration for the management of anaphylaxis or allergic reactions. Epinephrine autoinjector use may reduce barriers to epinephrine administration for the management of anaphylaxis in the ED.

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Trends, characteristics, and incidence of anaphylaxis in 2001-2010: A population-based study

Abstract: Background-Anaphylaxis is a potentially life-threatening systemic allergic reaction.

Cited by 121 publications

References 38 publications

Rate of recurrent anaphylaxis and associated risk factors among Olmsted County, Minnesota, residents

Rate of recurrent anaphylaxis and associated risk factors among Olmsted County, Minnesota, residents

Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies

Autoinjectors Preferred for Intramuscular Epinephrine in Anaphylaxis and Allergic Reactions

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