2022
DOI: 10.1016/j.cpcardiol.2022.101271
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Trends and Outcomes of ST-Segment-Elevation MI in Hospitalized Patients Without Standard Modifiable Cardiovascular Risk Factors

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Cited by 11 publications
(8 citation statements)
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“… 6 , 14 , 21 In addition, we report a 45% inhospital mortality for patients with STEMI and COVID-19, which is higher than reported in other studies during the pandemic, ranging from 18% to 33% 3 , 4 and significantly higher than the inhospital mortality reported for STEMI (up to 15%) before the COVID-19 pandemic. 22 , 23 These findings reiterate the significant impact the COVID-19 pandemic has had on the management of STEMI, possibly because of delay in presentation, delayed treatment given increased door-to-balloon time, 21 and additional myocardial injury risk and barriers from COVID-19 itself.…”
Section: Discussionmentioning
confidence: 84%
“… 6 , 14 , 21 In addition, we report a 45% inhospital mortality for patients with STEMI and COVID-19, which is higher than reported in other studies during the pandemic, ranging from 18% to 33% 3 , 4 and significantly higher than the inhospital mortality reported for STEMI (up to 15%) before the COVID-19 pandemic. 22 , 23 These findings reiterate the significant impact the COVID-19 pandemic has had on the management of STEMI, possibly because of delay in presentation, delayed treatment given increased door-to-balloon time, 21 and additional myocardial injury risk and barriers from COVID-19 itself.…”
Section: Discussionmentioning
confidence: 84%
“…In accordance with the younger age of the patients, the lower burden of co-morbidities and the lower prevalence of complex PCI, we report lower crude rate of adverse clinical outcomes in the SMuRF-less group. Most of the previous studies reported worse clinical outcomes among SMuRF-less patients [15] , [17] , [18] , [19] . In our cohort which included only patients treated with contemporary DES, even after adjustment to baseline demographics, co-morbidities and procedural characteristics, we did not find worse clinical outcome in the SMuRF-less group.…”
Section: Discussionmentioning
confidence: 89%
“…A recent global meta -analysis estimated prevalence of SMuRF-less patient as 12 % of ACS patients [17] . However, it should be noted that our cohort included patients undergoing PCI for ACS as well as CCS, the relative high prevalence of SMuRF-less patients in our cohort may also be partly related to the fact that even when presenting with STEMI, SMuRF-less patients are less likely to undergo PCI, potentially due to higher prevalence of MINOCA in this group [16] , [18] , [19] .…”
Section: Discussionmentioning
confidence: 96%
“…Prior studies have shown an association between hyperglycemic states and ST-Elevation MI (STEMI) in diabetic and nondiabetic patients [ 19 , 20 ]. Furthermore, it has been demonstrated to have a worse prognosis for short- and long-term outcomes [ 21 ]. However, DKA and its impact on MINOCA have yet to be previously investigated.…”
Section: Discussionmentioning
confidence: 99%