Trends and outcomes of minimally invasive surgery for gastrointestinal stromal tumors (GIST)

Robotic gastrointestinal stromal tumors surgery - initial results

“…[17] Gevorkian et al consider that the utilization of robotic-assisted resections of GI cancers is rapidly increasing with more frequent use in younger and healthier patients, where with the utilization of robotic-assisted resections, perioperative outcomes and oncologic safety have not been compromised. [18] In our initial group, the average size of the tumors was 5 cm, and we recorded no cases of injury and dissemination, due to the experience of the surgical team in laparoscopic surgery and correct instrument selection. These results coincide with modern minimally invasive and robotic approaches in the treatment of GIST, relying on the safety and reliability of surgical techniques, proven by a number of multicenter studies.…”

Low gastrointestinal tract bleeding secondary to low-grade gastrointestinal stromal tumor: case report

“…The treatment of this neoplasm is surgical and ideally consists of complete resection with negative margins (R0), depending on the location, size and involvement of neighboring structures, dissection of lymph nodes is not recommended, given the infrequent involvement and dissemination more frequently by hematogenous route with hepatic involvement. [2][3][4][5]7,8…”

“…GISTs generally affect subjects between the 4 th -6 th decades of life with a slight predominance in the male population, corresponding to approximately 0.1-0.3% of all neoplasms of the digestive tract with an estimated incidence and prevalence of 14.5 and 129 cases per million inhabitants respectively; representing 80% of gastrointestinal mesenchymal neoplasms. [1][2][3][4][5] Mitotic count and tumor size are the main prognostic factors identified related to disease progression and survival, it is difficult to predict their biological behavior (benign / malignant), other prognostic morphological variables consider mucosal involvement, presence of necrosis, hypercellularity, cellular pleomorphism and anatomical localization. [1][2][3][4][5][6][7][8][9][10] We present the case of a patient with low gastrointestinal tract bleeding secondary to a gastrointestinal stromal tumor, as well as her diagnostic clinical approach in a third-level medical unit, as well as a brief review of the literature.…”

“…[1][2][3][4][5] Mitotic count and tumor size are the main prognostic factors identified related to disease progression and survival, it is difficult to predict their biological behavior (benign / malignant), other prognostic morphological variables consider mucosal involvement, presence of necrosis, hypercellularity, cellular pleomorphism and anatomical localization. [1][2][3][4][5][6][7][8][9][10] We present the case of a patient with low gastrointestinal tract bleeding secondary to a gastrointestinal stromal tumor, as well as her diagnostic clinical approach in a third-level medical unit, as well as a brief review of the literature.…”

A narrative review of minimally invasive techniques for treatment of gastric gastrointestinal stromal tumors

“…According to National Comprehensive Cancer Network (NCCN) guidelines (10) all gastric GISTs ≥2 cm and lesions <2 cm with suspicious endoscopic ultrasound (EUS) features such as anechoic (cystic) spaces, irregular border, heterogeneity and ulceration, should be excised (11). In the last years, minimally invasive surgery has gained acceptance for the treatment of GISTs (12); initially this approach was limited to small tumors according to NCCN and European Society for Medical Oncology (ESMO) guidelines (13)(14)(15); more recently minimally invasive surgery has become accepted also for larger tumors (16). Laparoscopy is a safe and acceptable technique not only for GISTs less than 5 cm, but also for grater neoplasms (17).…”