Trend of geographical distribution of stomach cancer in Iran from 2004 to 2014

Abstract

Background Among different common types of cancer, gastric cancer (GC) is a worldwide health priority in both developing and developed countries. The aim of this study was to map the distribution of incident cases of GC in Iran to provide a geographical presentation of the incidence of the disease. Methods This study used the Iranian National Cancer Registry (INCR) data from 2004 to 2014. We calculated the crude and age-standardized incidence rates of GC for each province and also defined the frequency distribution of different types and locations of GC by the provinces. Results According to the results of the present study, the patients were predominantly male 49,907 (70.0%) and the most prevalent type of tumour was A1 (almost 96.4%) and C3‌ (2.0%). Also, a significant difference was observed between males and females in the distribution of the types of tumour (P < 0.001). In addition, a comparison of the distribution of the types of GC in Iran suggested that a significant difference exists between the provinces (P < 0.001). A significant difference was observed when the distribution of the location of GC tumors was compared between males and females and provinces (P < 0.001). Accordingly, pylori and cardia are the most common location of GC cancer among the study population (28.1% and 31.3% respectively). Conclusions The results of the current study suggested a higher rate of GC incidence in Iran when compared to the global figure in both females and males. Our study also revealed significant disparities between provinces with regard to the distribution of types, and location of GC. This may suggest involving different factors in GC in different parts of Iran. Further studies are needed to better understand the epidemiology and etiology of the disease in Iran.

Cancer incidence in Iran in 2016: A study based on the Iranian National Cancer Registry

“…The shift in rankings from the most common cancer in Iranian men in 2014 to the second most common in 2016 may be attributed to men exhibiting earlier onset, supported by our findings. 9,25 Behavioral factors like smoking and alcohol consumption in men might contribute to the higher lifetime risk of developing stomach cancer. 25 Prostate cancer, despite being the most common cancer in developed regions, 26 was the second most common in Iranian men in 2014.…”

“…9,25 Behavioral factors like smoking and alcohol consumption in men might contribute to the higher lifetime risk of developing stomach cancer. 25 Prostate cancer, despite being the most common cancer in developed regions, 26 was the second most common in Iranian men in 2014. 9 However, our 2016 data reveal a surge in prostate cancer incidence, making it the most common cancer among men.…”

High Frequency of Microsatellite Instability among Non-Metastatic Gastric Cancer

“…GC is one of the most prevalence malignancy in Iran and both genetic and environmental risk factors play a role in the etiology of the diseases 20 . Hence, study of the genetic risk factors to find favorable biomarker could be of interest.…”

Design and Development of an Intelligent System for Predicting 5-Year Survival in Gastric Cancer

“…This rising incidence in Iran is likely due to the recent demographic and epidemiological transitions in its population. 2 , 3 …”

“…This rising incidence in Iran is likely due to the recent demographic and epidemiological transitions in its population. 2,3 This malignancy imposes heavy costs on the health system and patients' families. Therefore, prevention and early screening of gastric cancer should be the main priority of the country's health system programs.…”