Tremor on Stimulation of the Midbrain Tegmentum after Degeneration of the Brachium Conjunctivum

Influence of Cerebellar Stimulation Upon Tremor of Tegmental Origin

“…1). It may be worth noting that this and previous descriptions of the tremor in the cat, with one exception [15], report the tremor usually maximally or exclusively ipsilateral to the side of midbrain stimulation. The tremor in the monkey, however, from both stimulation [8] and unilateral destructive lesion [13] is reported primarily contralateral to the lesion or stimulation.…”

“…Mettler [10] has attributed primary importance to them, although subsequently TFycis et al [15] have shown that bilateral degeneration of the brachium conjunctivum does not significantly affect the elicita tion of tremor from the midbrain and pontine tegmentum of the cat.…”

Parkinsonism with Oculogyric Crises. Stimulation and Partial Elimination of Periaqueductal Grey and Mesencephalic Tegmentum (Tegmentotomy)

“…B-470 of the N ational In stitu te of Neurological Diseases and Blindness of th e N ational In stitu te s of H ealth, D ept, of H ealth , E ducation and W elfare, Public H ealth Service. stim ulation experim ents of our laboratory (Spiegel, K letzkin and Szekely [12,13]; Folkerts and Spiegel [4]; Wycis, Szekely and Spiegel [17]; Alexander and Szekely [1]), as well as by sim ilar experim ents of Jenkner and Ward [6], This was a 30-ycar old white male who sulTered since 6 m onths with oculogyric crises and since 11 years with left sided static trem or and rigidity, more pronounced in the arm than in the leg, of unknow n etiology and uninfluenced by m edication. A ttacks of upw ard movem ents of the eyeballs occurred alm ost daily and lasted from 5 to 15 minutes.…”

Effects of Anti- And Pseudo-Parkinson Drugs on Shivering

“…The differences between them include the following: (1) Parkinson tremor involves alternating activity of antagonistic muscles (Wycis et al, 1957) whereas shivering may involve synchronous activity of flexors and extensors (Kawamura, 1961); (2) the limb tremor frequency is slower in Parkinson tremor, 4-7 cycles/sec. (Wachs and Boshes, 1961) than during shivering, 10-12 cycles/sec.…”