Treg-Derived Extracellular Vesicles: Roles in Diseases and Theranostics
Tingting Wu,
Lulu Wang,
Chen Gao
et al.
Abstract:Regulatory T cells (Tregs), a subset of CD4 + T cells, are indispensable in maintaining immune self-tolerance and have been utilized in various diseases. Treg-derived extracellular vesicles (Treg-EVs) have been discovered to play an important role in the mechanism of Treg functions. As cell-derived membranous particles, EVs carry multiple bioactive substances that possess tremendous potential for theranostics. Treg-EVs are involved in numerous physiological and pathological processes, carrying proteins and miR… Show more
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