Tree gum-based nanostructures and their biomedical applications

Kumar, K.P. Akshay; Ramakrishnan, Rohith K.; Černík, Miroslav

doi:10.1016/b978-0-323-90986-0.00008-x

Cited by 2 publications

(1 citation statement)

References 112 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although template-assisted green synthesis may be conducted to generate nanoparticles making use of tree gums, their delicate nature makes three-dimensional fabrication and application problematic. On the other hand, gum functional groups can be coupled with other biopolymers to aid conjugate sponge formation with better characteristics and targeted application potential [ 15 , 16 ]. In this way, gum kondagogu combines with another polysaccharide, sodium alginate, derived from marine algae.…”

Section: Introductionmentioning

confidence: 99%

Gum Hydrocolloids Reinforced Silver Nanoparticle Sponge for Catalytic Degradation of Water Pollutants

et al. 2022

Self Cite

View full text Add to dashboard Cite

The accumulation of organic contaminants including dyes in aquatic systems is of significant environmental concern, necessitating the development of affordable and sustainable materials for the treatment/elimination of these hazardous pollutants. Here, a green synthesis strategy has been used to develop a self-assembled gum kondagogu-sodium alginate bioconjugate sponge adorned with silver nanoparticles, for the first time. The properties of the nanocomposite sponge were then analyzed using FTIR, TGA, SEM, and MicroCT. The ensued biobased sponge exhibited hierarchical microstructure, open cellular pores, good shape memory, and mechanical properties. It merges the attributes of an open cellular porous structure with metal nanoparticles and are envisaged to be deployed as a sustainable catalytic system for reducing contaminants in the aqueous environment. This nanocomposite sponge showed enhanced catalytic effectiveness (km values up to 37 min−1 g−1 and 44 min−1 g−1 for methylene blue and 4-nitrophenol, respectively), antibacterial properties, reusability, and biodegradability (65% biodegradation in 28 days).

show abstract

Section: Introductionmentioning

confidence: 99%

Gum Hydrocolloids Reinforced Silver Nanoparticle Sponge for Catalytic Degradation of Water Pollutants

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

Zinc Pectinate-Sesbania Gum-Mediated Interpenetrating Polymer Network-Based Microbeads as a Candidate For Floating Drug Delivery of Esomeprazole

RAJPUT,

NANGARE,

CHAUDHARI

et al. 2024

Cellulose Chem. Technol.

View full text Add to dashboard Cite

This study aimed to develop esomeprazole-loaded zinc-pectinate-Sesbania gum floating microbeads, optionally supplemented with calcium silicate, as a gastro-retentive drug delivery system. The microbeads were produced using the ionic gelation method, with zinc acetate as the crosslinking agent, and were characterized through in vitro studies. The findings revealed that all formulations exhibited high drug encapsulation efficiency and sustained drug release profiles. Polymer ratios, calcium silicate incorporation, and the choice of low-density oils significantly influenced drug encapsulation efficiency and release kinetics. Notably, the B:6 batch, formulated with Sesbania gum and low methoxy pectin, demonstrated outstanding performance, releasing 95.89 ± 1.66% of the drug within 7 h, with a floating lag time of 1.18 ± 0.07 min, indicating promising in vitro gastro-retention capabilities. Analysis of P-XRD, FT-IR, SEM, and DSC data highlighted changes in crystallinity, drug–excipient compatibility, surface morphology, and thermal behavior of esomeprazole and esomeprazole-loaded microbeads. In conclusion, these floating microbeads represent a potential gastro-retentive drug delivery system, offering enhanced buoyancy and prolonged drug release, with potential therapeutic advantages for peptic ulcer management.

show abstract

Tree gum-based nanostructures and their biomedical applications

Cited by 2 publications

References 112 publications

Gum Hydrocolloids Reinforced Silver Nanoparticle Sponge for Catalytic Degradation of Water Pollutants

Gum Hydrocolloids Reinforced Silver Nanoparticle Sponge for Catalytic Degradation of Water Pollutants

Zinc Pectinate-Sesbania Gum-Mediated Interpenetrating Polymer Network-Based Microbeads as a Candidate For Floating Drug Delivery of Esomeprazole

Contact Info

Product

Resources

About